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Glycemic index
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==Application== ===Weight control=== Dietary replacement of saturated fats by carbohydrates with a low glycemic index may be beneficial for [[weight control]], whereas substitution with refined, high glycemic index carbohydrates is not.<ref name="pmid22157060">{{cite journal |vauthors=Brand-Miller J, Buyken AE |title=The glycemic index issue |journal=Curr. Opin. Lipidol. |volume=23 |issue=1 |pages=62β67 |year=2012 |pmid=22157060 |doi=10.1097/MOL.0b013e32834ec705 |s2cid=205829601 |url=https://zenodo.org/record/895683 |access-date=2019-06-27 |archive-date=2020-09-25 |archive-url=https://web.archive.org/web/20200925042210/https://zenodo.org/record/895683 |url-status=live }}</ref> However, a 2023 [[Cochrane review]] did not find that adoption of low glycemic index (or load) diets by people who are overweight or obese leads to more weight loss (and better fat control) than use of diets involving higher glycemic index/load or other strategies.<ref>{{Cite journal |title=Do low glycaemic index or low glycaemic load diets help people with overweight or obesity to lose weight? |url=https://www.cochrane.org/CD005105/ENDOC_do-low-glycaemic-index-or-low-glycaemic-load-diets-help-people-overweight-or-obesity-lose-weight |access-date=2023-06-23 |website=www.cochrane.org |doi=10.1002/14651858.CD005105.pub3 |pmid=37345841 |language=en|pmc=10313499 }}</ref> In clinical management of obesity, diets based on a low glycemic index/load appear to provide better glycemic and inflammatory control than ones based on a high glycemic index/load (and therefore could potentially be more effective in preventing obesity-related diseases).<ref name="pmid23786819">{{cite journal |vauthors=Schwingshackl L, Hoffmann G |title=Long-term effects of low glycemic index/load vs. high glycemic index/load diets on parameters of obesity and obesity-associated risks: a systematic review and meta-analysis |journal=Nutr Metab Cardiovasc Dis |volume=23 |issue=8 |pages=699β706 |year=2013 |pmid=23786819 |doi=10.1016/j.numecd.2013.04.008 |url=https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0059731/ |access-date=2017-05-30 |archive-date=2018-10-11 |archive-url=https://web.archive.org/web/20181011043251/https://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0059731/ |url-status=live }}</ref> In overweight and obese children, adoption of low glycemic index/load diets may not lead to weight loss but might potentially provide other benefits.<ref name="pmid26489667">{{cite journal |vauthors=Schwingshackl L, Hobl LP, Hoffmann G |title=Effects of low glycaemic index/low glycaemic load vs. high glycaemic index/ high glycaemic load diets on overweight/obesity and associated risk factors in children and adolescents: a systematic review and meta-analysis |journal=Nutr J |volume=14 |page=87 |year=2015 |pmid=26489667 |pmc=4618749 |doi=10.1186/s12937-015-0077-1 |doi-access=free }}</ref>
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