Editing Heck reaction (section)

==Stereoselectivity==
This [[coupling reaction]] is [[stereoselective]] with a propensity for [[trans isomer|trans]] coupling as the palladium halide group and the bulky organic residue move away from each other in the reaction sequence in a rotation step. The Heck reaction is applied industrially in the production of [[naproxen]] and the [[sunscreen]] component [[octyl methoxycinnamate]].  The naproxen synthesis includes a coupling between a brominated [[naphthalene]] compound with [[ethylene]]:<ref>{{cite journal | doi = 10.1139/cjc-79-5-6-1086 | title = The Heck reaction in the production of fine chemicals | year = 2001 |author1=De Vries |author2=Johannes G. | journal = [[Can. J. Chem.]] | volume = 79 | pages = 1086 | issue = 5–6}}</ref>

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[[File:Heck naproxen.svg|center|400px|The Heck reaction in Naproxen production]]
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! The Heck reaction in Naproxen production
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