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Inner ear
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===Development=== The human inner ear develops during week 4 of [[embryonic development]] from the [[auditory placode]], a thickening of the [[ectoderm]] which gives rise to the [[bipolar neuron]]s of the [[Scarpa's ganglion|cochlear]] and [[Spiral ganglion|vestibular ganglions]].<ref>{{cite book|last=Hyman|first=Libbie Henrietta |title=Hyman's comparative vertebrate anatomy |url=https://books.google.com/books?id=VKlWjdOkiMwC|access-date=2011-05-14|edition=3|year=1992|publisher=[[University of Chicago]] Press|isbn=0226870138|page=634}}</ref> As the auditory placode invaginates towards the embryonic [[mesoderm]], it forms the auditory vesicle or ''otocyst''. The [[auditory vesicle]] will give rise to the utricular and saccular components of the [[membranous labyrinth]]. They contain the sensory hair cells and [[otolith]]s of the [[macula of utricle]] and [[macula of saccule|of the saccule]], respectively, which respond to [[linear acceleration]] and the force of [[gravity]]. The utricular division of the auditory vesicle also responds to [[angular acceleration]], as well as the [[endolymphatic sac]] and [[Endolymphatic duct|duct]] that connect the saccule and utricle. Beginning in the fifth week of development, the auditory vesicle also gives rise to the [[cochlear duct]], which contains the spiral [[organ of Corti]] and the [[endolymph]] that accumulates in the membranous labyrinth.<ref name=USMLE>{{cite book|last=Brauer|first=Philip R. |title=Human embryology: the ultimate USMLE step 1 review |url=https://books.google.com/books?id=_Cb_XXR5HCQC|access-date=2011-05-14|year=2003|publisher=[[Elsevier]] Health Sciences|isbn=156053561X|page=61}}</ref> The [[Reissner's membrane|vestibular wall]] will separate the cochlear duct from the perilymphatic [[scala vestibuli]], a cavity inside the cochlea. The [[basilar membrane]] separates the cochlear duct from the [[scala tympani]], a cavity within the cochlear labyrinth. The lateral wall of the cochlear duct is formed by the [[spiral ligament]] and the [[stria vascularis]], which produces the [[endolymph]]. The [[hair cells]] develop from the lateral and medial ridges of the cochlear duct, which together with the [[tectorial membrane]] make up the organ of Corti.<ref name=USMLE />
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