Editing Langerhans cell (section)

===HIV===
Langerhans cells may be initial cellular targets in the sexual transmission of HIV,<ref>{{cite journal |doi=10.1016/j.jdermsci.2005.08.009 |title=The role of Langerhans cells in the sexual transmission of HIV |year=2005 |last1=Kawamura |first1=Tatsuyoshi |last2=Kurtz |first2=Stephen E. |last3=Blauvelt |first3=Andrew |last4=Shimada |first4=Shinji |journal=Journal of Dermatological Science |volume=40 |issue=3 |pages=147–55 |pmid=16226431}}</ref> and may be a target, reservoir, and vector of dissemination.<ref>{{cite journal |last1=Dezutter-Dambuyant |first1=C |last2=Charbonnier |first2=AS |last3=Schmitt |first3=D |title=Cellules dendritiques épithéliales et infection par HIV-1 in vivo et in vitro |trans-title=Epithelial dendritic cells and HIV-1 infection in vivo and in vitro |language=fr |journal=Pathologie Biologie |volume=43 |issue=10 |pages=882–8 |date=December 1995 |pmid=8786894}}</ref> Langerhans cells have been observed in foreskin, vaginal, and oral mucosa of humans; the lower concentrations in oral mucosa suggest that it is not a likely source of [[HIV]] infection relative to foreskin and vaginal mucosa.<ref name="pmid7558138">{{cite journal |pmid=7558138 |year=1995 |last1=Hussain |first1=LA |last2=Lehner |first2=T |title=Comparative investigation of Langerhans' cells and potential receptors for HIV in oral, genitourinary and rectal epithelia |volume=85 |issue=3 |pages=475–84 |pmc=1383923 |journal=Immunology}}</ref>