Editing Neural plate (section)

==Other animals==
The neural tube closes differently in various species, the distinctions between humans and chickens being some of the most studied. In humans, the neural tube fuses together from a central region of the embryo and moves outwards. In chickens, neural tube closure begins at the future midbrain region and it closes in both directions.<ref name="Gilbert" /> In birds and mammals, the closure does not occur at the same time.

In newt and general amphibian embryos, cell division is not a driving role in morphogenesis. Newt embryo cells are much larger and exhibit egg pigmentation to distinguish cells from each other. The newt neural plate doubles in length, decreases in apical width, and increases in thickness.<ref name=Jacobson>{{cite journal|last=Jacobson|first=Antone G.|title=Experimental Analyses of the Shaping of the Neural Plate and Tube|journal=American Zoologist|year=1991|volume=31|issue=4|pages=628–643|jstor=3883562|doi=10.1093/icb/31.4.628|doi-access=free}}</ref> The plate edges rise dorsally and fold toward the midline to form the neural tube. The apical surface area decreases.

In chicken embryos, while the neural plate increases in length and decreases in apical width, the thickness of the plate does not change drastically. As the neural plate progresses through the [[Hamburger-Hamilton stages]], the plate thickens until about HH6-7, when the neural plate begins to fold into tube form. The apical surface area increases during neurulation, unlike amphibian embryos.<ref name="Jacobson" /> In mouse embryos, there is a large convex-shaped curve to each side of the middle of the plate. This curve has to be reversed as the plate rolls together to form the neural tube.<ref name="Jacobson" />