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Patch clamp
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===Tissue sectioning=== Accurate tissue sectioning with [[Vibratome|compresstome vibratome]] or microtomes is essential, in addition to patch clamp methods. By supplying thin, uniform tissue slices, these devices provide optimal electrode implantation. To prepare tissues for patch clamp studies in a way that ensures accurate and dependable recordings, researchers can select between using vibratomes for softer tissues and microtomes for tougher structures.<ref>{{cite journal | pmid=2560557 | date=1989 | last1=Sakmann | first1=B. | last2=Edwards | first2=F. | last3=Konnerth | first3=A. | last4=Takahashi | first4=T. | title=Patch clamp techniques used for studying synaptic transmission in slices of mammalian brain | journal=Quarterly Journal of Experimental Physiology | volume=74 | issue=7 | pages=1107β1118 | doi=10.1113/expphysiol.1989.sp003336 | doi-access=free | hdl=11858/00-001M-0000-002C-270A-9 | hdl-access=free }}</ref> [[Leica Biosystems]], [[Carl Zeiss AG]] are the notable producer of these devices.
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