Editing Peripheral neuropathy (section)

===Mononeuritis multiplex===
'''Mononeuritis multiplex''', occasionally termed '''polyneuritis multiplex''', is simultaneous or sequential involvement of individual noncontiguous [[Spinal nerve|nerve trunk]]s,<ref>{{MedlinePlusEncyclopedia|000782|Multiple mononeuropathy}}</ref> either partially or completely, evolving over days to years and typically presenting with acute or subacute loss of sensory and motor function of individual [[nerves]]. The pattern of involvement is asymmetric.  However, as the disease progresses, deficit(s) becomes more confluent and symmetrical, making it difficult to differentiate from polyneuropathy.<ref>{{cite web|last1=Ball|first1=Derick A. |title=Peripheral Neuropathy|url=http://www.neuravite.com/peripheral-neuropathy|publisher=NeuraVite|access-date=24 March 2016}}</ref> Therefore, attention to the pattern of early symptoms is important.

Mononeuritis multiplex is sometimes associated with a deep, aching pain that worsens at night and frequently in the lower back, hip, or leg. In people with [[diabetes mellitus]], mononeuritis multiplex typically is encountered as acute, unilateral, and severe thigh pain followed by anterior muscle weakness and loss of knee reflex.{{medical citation needed|date=March 2016}}

[[Electrodiagnostic medicine]] studies will show multifocal sensory motor [[axon]]al neuropathy.{{citation needed|date=July 2022}}

It is caused by, or associated with, several medical conditions:
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* [[Diabetes mellitus]]
* [[Vasculitis|Vasculitides]]: [[polyarteritis nodosa]],<ref>{{cite journal | vauthors = Criado PR, Marques GF, Morita TC, de Carvalho JF | title = Epidemiological, clinical and laboratory profiles of cutaneous polyarteritis nodosa patients: Report of 22 cases and literature review | journal = Autoimmunity Reviews | volume = 15 | issue = 6 | pages = 558–63 | date = June 2016 | pmid = 26876385 | doi = 10.1016/j.autrev.2016.02.010 }}</ref><ref name="pmid25153486">{{cite journal | vauthors = Samson M, Puéchal X, Devilliers H, Ribi C, Cohen P, Bienvenu B, Terrier B, Pagnoux C, Mouthon L, Guillevin L | title = Mononeuritis multiplex predicts the need for immunosuppressive or immunomodulatory drugs for EGPA, PAN and MPA patients without poor-prognosis factors | journal = Autoimmunity Reviews | volume = 13 | issue = 9 | pages = 945–53 | date = September 2014 | pmid = 25153486 | doi = 10.1016/j.autrev.2014.08.002 }}</ref> [[granulomatosis with polyangiitis]]<ref name="pmid25153486"/> and [[eosinophilic granulomatosis with polyangiitis]].<ref name="pmid25153486"/> This results in [[vasculitic neuropathy]].
* Immune-mediated diseases, such as [[rheumatoid arthritis]],<ref name="pmid2835572">{{cite journal | vauthors = Hellmann DB, Laing TJ, Petri M, Whiting-O'Keefe Q, Parry GJ | title = Mononeuritis multiplex: the yield of evaluations for occult rheumatic diseases | journal = Medicine | volume = 67 | issue = 3 | pages = 145–53 | date = May 1988 | pmid = 2835572 | doi = 10.1097/00005792-198805000-00001 | s2cid = 24059700 | doi-access = free }}</ref> [[systemic lupus erythematosus]] (SLE)
* Infections:  [[leprosy]], [[lyme disease]], [[parvovirus B19]],<ref>{{cite journal | vauthors = Lenglet T, Haroche J, Schnuriger A, Maisonobe T, Viala K, Michel Y, Chelbi F, Grabli D, Seror P, Garbarg-Chenon A, Amoura Z, Bouche P | title = Mononeuropathy multiplex associated with acute parvovirus B19 infection: characteristics, treatment and outcome | journal = Journal of Neurology | volume = 258 | issue = 7 | pages = 1321–6 | date = July 2011 | pmid = 21287183 | doi = 10.1007/s00415-011-5931-2 | s2cid = 8145505 }}</ref> [[HIV]]<ref>{{cite journal | vauthors = Kaku M, Simpson DM | title = HIV neuropathy | journal = Current Opinion in HIV and AIDS | volume = 9 | issue = 6 | pages = 521–6 | date = November 2014 | pmid = 25275705 | doi = 10.1097/COH.0000000000000103 | s2cid = 3023845 | doi-access = free }}</ref>
* [[Sarcoidosis]]<ref>{{cite journal | vauthors = Vargas DL, Stern BJ | title = Neurosarcoidosis: diagnosis and management | journal = Seminars in Respiratory and Critical Care Medicine | volume = 31 | issue = 4 | pages = 419–27 | date = August 2010 | pmid = 20665392 | doi = 10.1055/s-0030-1262210 | s2cid = 260321346 }}</ref>
* [[Cryoglobulinemia]]<ref>{{cite journal | vauthors = Cacoub P, Comarmond C, Domont F, Savey L, Saadoun D | title = Cryoglobulinemia Vasculitis | journal = The American Journal of Medicine | volume = 128 | issue = 9 | pages = 950–5 | date = September 2015 | pmid = 25837517 | doi = 10.1016/j.amjmed.2015.02.017 | s2cid = 12560858 | url = https://hal.sorbonne-universite.fr/hal-01142000/file/Cacoub_Cryoglobulinemia.pdf | url-access =  | url-status =  | archive-url =  | archive-date =  }}</ref>
* Reactions to exposure to chemical agents, including [[trichloroethylene]] and [[dapsone]]{{medical citation needed|date=March 2016}}
* Rarely, following the sting of certain [[jellyfish]], such as the [[sea nettle]]{{medical citation needed|date=March 2016}}
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