Editing Plasma cell (section)

===Immature plasma cells===
[[File:Plasmablast, Wright stain.png|thumb|Plasmablast, [[Wright stain]].]]
The most immature blood cell that is considered of plasma cell lineage is the plasmablast.<ref name="isbn0-7817-6507-2">{{cite book | vauthors = Glader B, Greer JG, Foerster J, Rodgers GC, Paraskevas F |title=Wintrobe's Clinical Hematology, 2-Vol. Set |publisher=Lippincott Williams & Wilkins |location=Hagerstwon, MD |year=2008 |pages=347 |isbn=978-0-7817-6507-7 }}</ref> Plasmablasts secrete more antibodies than B cells, but less than plasma cells.<ref name="Walport-2008">{{cite book |vauthors = Walport M, Murphy K, Janeway C, Travers PJ |title=Janeway's immunobiology |publisher=Garland Science |location=New York |year=2008 |pages=[https://archive.org/details/janewaysimmunobi00murp/page/387 387–388] |isbn=978-0-8153-4123-9 |url-access=registration |url=https://archive.org/details/janewaysimmunobi00murp/page/387 }}</ref> They divide rapidly and are still capable of internalizing antigens and presenting them to T cells.<ref name="Walport-2008" /> A cell may stay in this state for several days, and then either die or irrevocably differentiate into a mature, fully differentiated plasma cell.<ref name="Walport-2008" /> Differentiation of mature B cells into plasma cells is dependent upon the transcription factors [[Blimp-1]]/[[PRDM1]], [[BCL6]], and [[IRF4]].<ref name="Merino Tejero-2020" />