Editing Precocious puberty (section)

=== Isosexual and heterosexual ===
Generally, patients with precocious puberty develop [[phenotype|phenotypically]] appropriate [[secondary sexual characteristic]]s. This is called ''[[isosexual]]'' precocity.<ref name=":0">{{cite journal|last1=Jarzabek-Bielecka|first1=G|last2=Warchoł-Biedermann|first2=K|last3=Sowińska|first3=E|last4=Wachowiak-Ochmańska|first4=K|title=[Precocious puberty].|journal=Ginekologia Polska|date=April 2011|volume=82|issue=4|pages=281–6|pmid=21735696}}</ref>

In some cases, a patient may develop characteristics of the opposite sex. For example, a male may [[gynecomastia|develop breasts]] and other feminine characteristics, while a female may develop a deepened voice and facial hair. This is called ''heterosexual'' or ''contrasexual'' precocity. It is very rare in comparison to isosexual precocity and is usually the result of unusual circumstances. As an example, children with a very rare genetic condition called [[aromatase excess syndrome]] – in which exceptionally high circulating levels of estrogen are present – usually develop precocious puberty. Males and females are hyper-feminized by the syndrome.<ref name=":0" /> The "opposite" case would be the hyper-masculinisation of both male and female patients with [[congenital adrenal hyperplasia due to 21-hydroxylase deficiency|congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency]], in which there is an excess of androgens. Thus, in the aromatase excess syndrome the precocious puberty is isosexual in females and heterosexual in males, whilst in the CAH it is isosexual in males and heterosexual in females.{{citation needed|date=August 2020}}