Editing Randomized controlled trial (section)

=== Trial registration ===
In 2004, the [http://www.icmje.org/ International Committee of Medical Journal Editors] (ICMJE) announced that all trials starting enrolment after July 1, 2005, must be registered prior to consideration for publication in one of the 12 member journals of the committee.<ref name="pmid15356289">{{Cite journal |vauthors=De Angelis C, Drazen JM, Frizelle FA, Haug C, Hoey J, Horton R, Kotzin S, Laine C, Marusic A, Overbeke AJ, Schroeder TV, Sox HC, Van Der Weyden MB |date=September 2004 |title=Clinical trial registration: a statement from the International Committee of Medical Journal Editors |journal=The New England Journal of Medicine |volume=351 |issue=12 |pages=1250–1251 |doi=10.1056/NEJMe048225 |pmid=15356289 |doi-access=free}}</ref> However, trial registration may still occur late or not at all.<ref name="pmid22147862">{{Cite journal |vauthors=Law MR, Kawasumi Y, Morgan SG |date=December 2011 |title=Despite law, fewer than one in eight completed studies of drugs and biologics are reported on time on ClinicalTrials.gov |journal=Health Affairs |volume=30 |issue=12 |pages=2338–2345 |doi=10.1377/hlthaff.2011.0172 |pmid=22147862 |doi-access=free}}</ref><ref name="pmid19724045">{{Cite journal |vauthors=Mathieu S, Boutron I, Moher D, Altman DG, Ravaud P |date=September 2009 |title=Comparison of registered and published primary outcomes in randomized controlled trials |journal=JAMA |volume=302 |issue=9 |pages=977–984 |doi=10.1001/jama.2009.1242 |pmid=19724045 |doi-access=free}}</ref>
Medical journals have been slow in adapting policies requiring mandatory clinical trial registration as a prerequisite for publication.<ref>{{Cite journal |vauthors=Bhaumik S, Biswas T |date=March 2013 |title=Editorial policies of MEDLINE indexed Indian journals on clinical trial registration |journal=Indian Pediatrics |volume=50 |issue=3 |pages=339–340 |doi=10.1007/s13312-013-0092-2 |pmid=23680610 |s2cid=40317464}}</ref>