Editing Serotonin transporter (section)

===Ligands===
* [[DASB]]
* compound 4b: ''K''i = 17 pM; 710-fold and 11,100-fold selective over DAT and NET<ref name="pmid15686927">{{cite journal | vauthors = Tamagnan G, Alagille D, Fu X, Kula NS, Baldessarini RJ, Innis RB, Baldwin RM | title = Synthesis and monoamine transporter affinity of new 2beta-carbomethoxy-3beta-[4-(substituted thiophenyl)]phenyltropanes: discovery of a selective SERT antagonist with picomolar potency | journal = Bioorganic & Medicinal Chemistry Letters | volume = 15 | issue = 4 | pages = 1131–1133 | date = February 2005 | pmid = 15686927 | doi = 10.1016/j.bmcl.2004.12.014 }}</ref>
* compound (+)-12a: ''K''i = 180 pM at hSERT; >1000-fold selective over hDAT, hNET, 5-HT<sub>1A</sub>, and 5-HT<sub>6</sub>.<ref name="pmid16162005">{{cite journal | vauthors = Mattson RJ, Catt JD, Denhart DJ, Deskus JA, Ditta JL, Higgins MA, Marcin LR, Sloan CP, Beno BR, Gao Q, Cunningham MA, Mattson GK, Molski TF, Taber MT, Lodge NJ | title = Conformationally restricted homotryptamines. 2. Indole cyclopropylmethylamines as selective serotonin reuptake inhibitors | journal = Journal of Medicinal Chemistry | volume = 48 | issue = 19 | pages = 6023–6034 | date = September 2005 | pmid = 16162005 | doi = 10.1021/jm0503291 }}</ref> [[Bioisostere|Isostere]]s<ref name="pmid17766113">{{cite journal | vauthors = Dalton King H, Denhart DJ, Deskus JA, Ditta JL, Epperson JR, Higgins MA, Kung JE, Marcin LR, Sloan CP, Mattson GK, Molski TF, Krause RG, Bertekap RL, Lodge NJ, Mattson RJ, Macor JE | title = Conformationally restricted homotryptamines. Part 4: Heterocyclic and naphthyl analogs of a potent selective serotonin reuptake inhibitor | journal = Bioorganic & Medicinal Chemistry Letters | volume = 17 | issue = 20 | pages = 5647–5651 | date = October 2007 | pmid = 17766113 | doi = 10.1016/j.bmcl.2007.07.083 }}</ref>
* 3-''cis''-(3-Aminocyclopentyl)indole 8a: ''K''i = 220 pM<ref>{{cite journal | vauthors = King HD, Meng Z, Deskus JA, Sloan CP, Gao Q, Beno BR, Kozlowski ES, Lapaglia MA, Mattson GK, Molski TF, Taber MT, Lodge NJ, Mattson RJ, Macor JE | title = Conformationally restricted homotryptamines. Part 7: 3-cis-(3-aminocyclopentyl)indoles as potent selective serotonin reuptake inhibitors | journal = Journal of Medicinal Chemistry | volume = 53 | issue = 21 | pages = 7564–7572 | date = November 2010 | pmid = 20949929 | doi = 10.1021/jm100515z }}</ref>
* allosteric modulator: 3′-Methoxy-8-methyl-spiro{8-azabicyclo[3.2.1]octane-3,5′(4′H)-isoxazole} (compound 7a)<ref>{{cite journal | vauthors = Dallanoce C, Canovi M, Matera C, Mennini T, De Amici M, Gobbi M, De Micheli C | title = A novel spirocyclic tropanyl-Δ²-isoxazoline derivative enhances citalopram and paroxetine binding to serotonin transporters as well as serotonin uptake | journal = Bioorganic & Medicinal Chemistry | volume = 20 | issue = 21 | pages = 6344–6355 | date = November 2012 | pmid = 23022052 | doi = 10.1016/j.bmc.2012.09.004 }}</ref>
* allosteric modulator: ''p''-Trifluoromethyl-[[methcathinone]]<ref name="pmid31028773">{{cite journal | vauthors = Niello M, Cintulova D, Hellsberg E, Jäntsch K, Holy M, Ayatollahi LH, Cozzi NV, Freissmuth M, Sandtner W, Ecker GF, Mihovilovic MD, Sitte HH | title = para-Trifluoromethyl-methcathinone is an allosteric modulator of the serotonin transporter | journal = Neuropharmacology | volume = 161 | pages = 107615 | date = December 2019 | pmid = 31028773 | doi = 10.1016/j.neuropharm.2019.04.021 | s2cid = 128363044 | doi-access =  }}</ref>