Editing Signal peptide (section)

==Secretion efficiency determination==

Signal peptides are extremely heterogeneous, many prokaryotic and eukaryotic ones are functionally interchangeable within or between species and all determine protein secretion efficiency.<ref name="pmid23124363">{{cite journal | vauthors = Kober L, Zehe C, Bode J | title = Optimized signal peptides for the development of high expressing CHO cell lines | journal = Biotechnology and Bioengineering | volume = 110 | issue = 4 | pages = 1164–73 | date = April 2013 | pmid = 23124363 | doi = 10.1002/bit.24776 | s2cid = 449870 }}</ref><ref name="pmid4032478">{{cite journal | vauthors = von Heijne G | title = Signal sequences. The limits of variation | journal = Journal of Molecular Biology | volume = 184 | issue = 1 | pages = 99–105 | date = July 1985 | pmid = 4032478 | doi = 10.1016/0022-2836(85)90046-4 | author-link = Gunnar von Heijne }}</ref><ref>{{cite journal | vauthors = Molino JV, de Carvalho JC, Mayfield SP | title = Comparison of secretory signal peptides for heterologous protein expression in microalgae: Expanding the secretion portfolio for Chlamydomonas reinhardtii | journal = PLOS ONE | volume = 13 | issue = 2 | pages = e0192433 | date = 2018-02-06 | pmid = 29408937 | pmc = 5800701 | doi = 10.1371/journal.pone.0192433 | bibcode = 2018PLoSO..1392433M | doi-access = free }}</ref>