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Tinea versicolor
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==Treatment== Treatments for tinea versicolor include: * [[Topical]] [[Antifungal drug|antifungal medications]] containing [[Selenium disulfide|selenium sulfide]] are often recommended.<ref name="Athlete"/> [[Ketoconazole]] ([[Nizoral]] ointment and shampoo) is another treatment. It is normally applied to dry skin and washed off after 20 minutes, repeated daily for two weeks.{{citation needed|date=May 2020}} [[Ciclopirox]] (ciclopirox olamine) is an alternative treatment to ketoconazole, as it suppresses growth of the yeast ''Malassezia furfur''. Initial results show similar efficacy to ketoconazole with a relative increase in subjective symptom relief due to its inherent anti-inflammatory properties.<ref>{{cite journal |vauthors=Ratnavel RC, Squire RA, Boorman GC |title=Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis |journal=J Dermatolog Treat |volume=18 |issue=2 |pages=88β96 |year=2007 |pmid=17520465 |doi=10.1080/16537150601092944|s2cid=34852507 }}</ref> Other topical antifungal agents such as [[clotrimazole]], [[miconazole]], [[terbinafine]], or [[zinc pyrithione]] can lessen symptoms in some patients.<ref>{{cite journal|title = Management of Seborrheic Dermatitis and Pityriasis Versicolor|last = Faergemann|first = Jan|journal = [[Am. J. Clin. Dermatol.]]|year = 2000|volume = 1|issue = 2|pages = 75β80|pmid = 11702314|doi = 10.2165/00128071-200001020-00001|s2cid = 43516330}}</ref> Additionally, [[hydrogen peroxide]] has been known to lessen symptoms and, on certain occasions, remove the problem, although permanent scarring has occurred with this treatment in some people.{{Citation needed|date=June 2009}} Clotrimazole is also used combined with selenium sulfide.{{citation needed|date=February 2023}} * Oral medications are viewed as a second-line of treatment for pityriasis versicolor in the event of widespread, severe, recalcitrant or recurrent cases. Systemic therapies include [[itraconazole]] (200 mg daily for seven days) and [[fluconazole]] (150 to 300 mg weekly dose for 2 to 4 weeks) that are preferred to oral ketoconazole which is no longer approved due to its potential hepatotoxic side effects.<ref name="Karray McKinney 2021 p. ">{{citation | last1=Karray | first1=M | last2=McKinney | first2=WP | title=Tinea Versicolor | chapter=article-30211 | publisher=StatPearls Publishing | publication-place=Treasure Island (FL) | year=2021 | pmid=29494106 | url=http://www.ncbi.nlm.nih.gov/books/NBK482500/ | access-date=2021-08-07 | page= | archive-date=2021-10-17 | archive-url=https://web.archive.org/web/20211017171015/https://www.ncbi.nlm.nih.gov/books/NBK482500/ | url-status=live }}[[File:CC-BY icon.svg|50px]] Text was copied from this source, which is available under a [https://creativecommons.org/licenses/by/4.0/ Creative Commons Attribution 4.0 International License] {{Webarchive|url=https://web.archive.org/web/20171016050101/https://creativecommons.org/licenses/by/4.0/ |date=2017-10-16 }}.</ref> The single-dose regimens and [http://medical-dictionary.thefreedictionary.com/pulse+therapy pulse therapy] regimens can be made more effective by having the patient exercise 1β2 hours after the dose, to induce sweating. The sweat is allowed to evaporate, and showering is delayed for a day, leaving a film of the medication on the skin.<ref>[http://www.fpnotebook.com/ID/Pharm/Ktcnzl.htm Ketoconazole] {{Webarchive|url=https://web.archive.org/web/20210128022806/https://fpnotebook.com/ID/Pharm/Ktcnzl.htm |date=2021-01-28 }}. Fpnotebook.com. Retrieved on 2016-10-14.</ref>
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