Editing Transfer RNA (section)

== Nomenclature ==
A tRNA is commonly named by its intended amino acid (e.g. {{nowrap|tRNA-Asn}}), by its anticodon sequence (e.g. {{nowrap|tRNA(GUU)}}), or by both (e.g. {{nowrap|tRNA-Asn(GUU)}} or {{nowrap|tRNA{{sup sub|Asn|GUU}}}}).<ref>{{cite journal |last1=Parisien |first1=Marc |last2=Wang |first2=Xiaoyun |last3=Pan |first3=Tao |title=Diversity of human tRNA genes from the 1000-genomes project |journal=RNA Biology |date=December 2013 |volume=10 |issue=12 |pages=1853–1867 |doi=10.4161/rna.27361|doi-access=free |pmid=24448271 |pmc=3917988 }}</ref> These two features describe the main function of the tRNA, but do not actually cover the whole diversity of tRNA variation; as a result, numerical suffixes are added to differentiate.<ref>{{cite journal |last1=Chan |first1=PP |last2=Lowe |first2=TM |title=GtRNAdb 2.0: an expanded database of transfer RNA genes identified in complete and draft genomes. |journal=Nucleic Acids Research |date=4 January 2016 |volume=44 |issue=D1 |pages=D184-9 |doi=10.1093/nar/gkv1309 |pmid=26673694|doi-access=free |pmc=4702915 }}</ref> tRNAs intended for the same amino acid are called "isotypes"; these with the same anticodon sequence are called "isoacceptors"; and these with both being the same but differing in other places are called "isodecoders".<ref>{{cite journal |last1=Hughes |first1=Laetitia A. |last2=Rudler |first2=Danielle L. |last3=Siira |first3=Stefan J. |last4=McCubbin |first4=Tim |last5=Raven |first5=Samuel A. |last6=Browne |first6=Jasmin M. |last7=Ermer |first7=Judith A. |last8=Rientjes |first8=Jeanette |last9=Rodger |first9=Jennifer |last10=Marcellin |first10=Esteban |last11=Rackham |first11=Oliver |last12=Filipovska |first12=Aleksandra |title=Copy number variation in tRNA isodecoder genes impairs mammalian development and balanced translation |journal=Nature Communications |date=18 April 2023 |volume=14 |issue=1 |page=2210 |doi=10.1038/s41467-023-37843-9|doi-access=free |pmid=37072429 |pmc=10113395 |bibcode=2023NatCo..14.2210H }}</ref>