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Quorum sensing
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===Applications=== Applications of quorum quenching that have been exploited by humans include the use of AHL-degrading bacteria in aquacultures to limit the spread of diseases in aquatic populations of fish, mollusks and crustaceans.<ref name=":42">{{cite journal | vauthors = Grandclément C, Tannières M, Moréra S, Dessaux Y, Faure D | title = Quorum quenching: role in nature and applied developments | journal = FEMS Microbiology Reviews | volume = 40 | issue = 1 | pages = 86–116 | date = January 2016 | pmid = 26432822 | doi = 10.1093/femsre/fuv038 | doi-access = free }}</ref> This technique has also been translated to agriculture, to restrict the spread of pathogenic bacteria that use quorum sensing in plants.<ref name=":42" /><ref>{{cite journal | vauthors = Galloway WR, Hodgkinson JT, Bowden S, Welch M, Spring DR | title = Applications of small molecule activators and inhibitors of quorum sensing in Gram-negative bacteria | journal = Trends in Microbiology | volume = 20 | issue = 9 | pages = 449–458 | date = September 2012 | pmid = 22771187 | doi = 10.1016/j.tim.2012.06.003 }}</ref> Anti-[[biofouling]] is another process that exploits quorum quenching bacteria to mediate the dissociation of unwanted biofilms aggregating on wet surfaces, such as medical devices, transportation infrastructure and water systems.<ref name=":42" /><ref name=":62">{{Cite journal| vauthors = Liu CX, Zhang DR, He Y, Zhao XS, Bai R |title=Modification of membrane surface for anti-biofouling performance: Effect of anti-adhesion and anti-bacteria approaches|journal=[[Journal of Membrane Science]]|volume=346|issue=1|pages=121–130|doi=10.1016/j.memsci.2009.09.028|year=2010}}</ref> Quorum quenching is recently studied for the control of fouling and emerging contaminants in electro membrane bioreactors (eMBRs) for the advanced treatment of wastewater.<ref name=":43">{{cite journal | vauthors = Borea L, Naddeo V, Belgiorno V, Choo KH | title = Control of quorum sensing signals and emerging contaminants in electrochemical membrane bioreactors | journal = Bioresource Technology | volume = 269 | pages = 89–95 | date = December 2018 | pmid = 30153550 | doi = 10.1016/j.biortech.2018.08.041 | bibcode = 2018BiTec.269...89B | s2cid = 52134789 }}</ref> Extracts of several traditional medicinal herbs display quorum quenching activity, and have potential antibacterial applications.<ref>{{cite journal | vauthors = Moradi F, Hadi N | title = Quorum-quenching activity of some Iranian medicinal plants | journal = New Microbes and New Infections | volume = 42 | pages = 100882 | date = July 2021 | pmid = 34094582 | pmc = 8165558 | doi = 10.1016/j.nmni.2021.100882 }}</ref><ref>{{cite journal | vauthors = Moradi F, Hadi N, Bazargani A | title = Evaluation of quorum-sensing inhibitory effects of extracts of three traditional medicine plants with known antibacterial properties | journal = New Microbes and New Infections | volume = 38 | pages = 100769 | date = November 2020 | pmid = 33194208 | pmc = 7644747 | doi = 10.1016/j.nmni.2020.100769 }}</ref>
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