Editing DNA sequencing (section)

=== Microscopy-based techniques ===
{{Main|Transmission electron microscopy DNA sequencing}}
This approach directly visualizes the sequence of DNA molecules using electron microscopy. The first identification of DNA base pairs within intact DNA molecules by enzymatically incorporating modified bases, which contain atoms of increased atomic number, direct visualization and identification of individually labeled bases within a synthetic 3,272 base-pair DNA molecule and a 7,249 base-pair viral genome has been demonstrated.<ref>{{cite journal | vauthors = Bell DC, Thomas WK, Murtagh KM, Dionne CA, Graham AC, Anderson JE, Glover WR | title = DNA Base Identification by Electron Microscopy | journal = Microscopy and Microanalysis | volume = 18 | issue = 5 | pages = 1049–53 | date = 9 October 2012 | pmid = 23046798 | doi = 10.1017/S1431927612012615 | bibcode = 2012MiMic..18.1049B | s2cid = 25713635 }}</ref>