Editing Doctor Octopus (section)

==In other media==
===Television===
* Doctor Octopus appears in ''[[Spider-Man (1967 TV series)|Spider-Man]]'' (1967), voiced by Vernon Chapman.<ref name="TVoDO">{{cite web |title=Doctor Octopus Voices (Spider-Man) |url=http://www.behindthevoiceactors.com/characters/Spider-Man/Doctor-Octopus/ |publisher=Behind The Voice Actors |postscript=. A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information.}}</ref>
* Doctor Octopus appears in the ''[[Spider-Man (1981 TV series)|Spider-Man]]'' (1981) episode "Bubble, Bubble, Oil and Trouble", voiced by [[G. Stanley Jones]].<ref name="TVoDO"/>
* Doctor Octopus appears in ''[[The Incredible Hulk (1982 animated series)|The Incredible Hulk]]'' episode "Tomb of the Unknown Hulk", voiced by [[Michael Bell (actor)|Michael Bell]].<ref name="TVoDO"/>
* Doctor Octopus appears in the ''[[Spider-Man and His Amazing Friends]]'' episode "Spidey Meets the Girl of Tomorrow", voiced again by Michael Bell.<ref name="TVoDO"/>
* Doctor Octopus appears in ''[[Spider-Man: The Animated Series]]'', voiced by [[Efrem Zimbalist Jr.]]<ref name="TVoDO"/> This version sports a German accent and was Peter Parker's teacher at science camp when the latter was a child. Despite having turned to villainy years later, Octavius still refers to himself as Parker's teacher following their reunion. Throughout the series, he battles Spider-Man while serving as a member of the [[Kingpin (character)|Kingpin]]'s [[Sinister Six|Insidious Six]].
* Otto Octavius / Doctor Octopus appears in ''[[The Spectacular Spider-Man (TV series)|The Spectacular Spider-Man]]'', voiced by [[Peter MacNicol]].<ref name="TVoDO" /> This version is initially a timid, weak-willed scientist and inventor at [[Oscorp]]. Following a lab accident caused by the [[Norman Osborn|Green Goblin]], Octavius is fused with his tentacle harness and becomes more aggressive and violent. After being defeated by Spider-Man, he forms the Sinister Six to seek revenge against him, only to be defeated by the [[Symbiote (comics)|symbiote]]-possessed Spider-Man. In the second season, Octavius adopts the Master Planner alias as he re-forms the Sinister Six and attempts to take over the world by hacking into the [[Federal Bureau of Investigation|FBI]]'s servers, only to be thwarted by Spider-Man. He later competes with [[Tombstone (character)|Tombstone]] and [[Silvermane]] for control of New York's criminal underworld until all three are defeated by Spider-Man.
* Otto Octavius / Doctor Octopus appears in ''[[Ultimate Spider-Man (TV series)|Ultimate Spider-Man]]'', voiced by [[Tom Kenny]].<ref>{{cite web|last=Webb|first=Charles|title=Interview: Tom Kenny on the Hilarious Creepiness of 'Adventure Time's' Ice King|url=http://geek-news.mtv.com/2011/09/27/interview-tom-kenny-on-the-hilarious-creepiness-of-adventure-times-ice-king/|archive-url=https://web.archive.org/web/20111003150828/http://geek-news.mtv.com/2011/09/27/interview-tom-kenny-on-the-hilarious-creepiness-of-adventure-times-ice-king|url-status=dead|archive-date=October 3, 2011|publisher=MTV|access-date=September 27, 2011}}</ref><ref name="TVoDO" /> This version was an Oscorp scientist who was left paralyzed and entirely dependent on four mechanical tentacles built by [[Norman Osborn]] following a lab accident. Throughout the first season, Octavius primarily operates from the shadows, employing supervillains to capture Spider-Man for his DNA on Norman's behalf; with one of his experiments with Spider-Man's DNA leading to the [[Venom (character)|Venom]] symbiote's creation. Octavius eventually betrays Norman by forcibly turning him into the Green Goblin and escapes after his underwater lab is destroyed. In the second season, Octavius forms the Sinister Six in an attempt to eliminate Spider-Man, only to be defeated. After making minor appearances in the third season, Octavius returns in the fourth season, having allied with [[Hydra (comics)|Hydra]] to form a new iteration of the Sinister Six and create the synthezoid [[Ben Reilly|Scarlet Spider]] to serve as a spy within Spider-Man's team. While leading an attack on the Triskelion, Octavius discovers Spider-Man's secret identity, but is betrayed by Scarlet Spider, who foils his plan. Octavius later reclaims his nanotech and gives himself a younger body before reforming the Sinister Six once more and taking Spider-Man's allies hostage. However, Spider-Man defeats the Sinister Six and persuades Octavius to surrender.
** Additionally, two [[Multiverse (Marvel Comics)|alternate reality]] versions of Octavius, a medieval variant called the '''Alchemist''' and a Wild West outlaw called '''Doc Ock Holliday''', appear in the episodes "The Spider-Verse" and "Return to the Spider-Verse", both also voiced by Kenny.<ref name="btva">{{cite web |title=The Kraken / The Alchemist Voice - ''Ultimate Spider-Man'' (TV Show) |url=https://www.behindthevoiceactors.com/tv-shows/Ultimate-Spider-Man/The-Kraken-The-Alchemist/ |access-date=August 14, 2024 |publisher=Behind The Voice Actors}} A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information.</ref>
* Doctor Octopus appears in the ''[[Hulk and the Agents of S.M.A.S.H.]]'' episode "The Venom Inside", voiced again by Tom Kenny.<ref name="TVoDO"/>
* Doctor Octopus appears in ''[[Lego Marvel Super Heroes: Maximum Overload]]'', voiced again by Tom Kenny.<ref name="TVoDO" />
* Doctor Octopus appears in ''[[Marvel Disk Wars: The Avengers]]'', voiced by [[Dai Matsumoto]] in the original Japanese version and by [[Dave Wittenberg]] in the English dub.<ref name="TVoDO"/>
* Otto Octavius / Doctor Octopus appears in ''[[Spider-Man (2017 TV series)|Spider-Man]]'' (2017), voiced by [[Scott Menville]].<ref>{{cite web |last=Busch |first=Jenna |date=July 14, 2017 |title=Marvel's Animated Spider-Man Voice Cast and Premiere Date |url=http://www.comingsoon.net/tv/news/869243-marvels-animated-spider-man-voice-cast-and-premiere-date |website=comingsoon.net}}</ref><ref name="TVoDO" /> This version is an arrogant but brilliant 19-year-old prodigy who was picked on by a jock and abused by his father Torbert (voiced by [[Charlie Adler]]<ref name="btva2">{{cite web |title=Father Octavius Voice - ''Spider-Man'' (2017) (TV Show) |url=https://www.behindthevoiceactors.com/tv-shows/Spider-Man-2017/Father-Octavius/ |access-date=August 14, 2024 |publisher=Behind The Voice Actors}} A green check mark indicates that a role has been confirmed using a screenshot (or collage of screenshots) of a title's list of voice actors and their respective characters found in its credits or other reliable sources of information.</ref>) while growing up. Introduced in the first season, Octavius works as a professor at Horizon High until his tentacle harness becomes fused to his spine following a lab accident caused by the [[Crimson Dynamo]]. Following this, he tries to use his newfound abilities to become a superhero under Spider-Man's guidance until his ego eventually causes him to become a supervillain and form the Sinister Six, though they are defeated by Spider-Man and [[Harry Osborn]] / [[Hobgoblin (comics)|Hobgoblin]]. In the second season, Octavius is released from prison, claiming that he wants to redeem himself, and returns to being a professor at Horizon High. However, he secretly places a bounty on Spider-Man. After being defeated, Octavius is left in a [[coma]] and his consciousness temporarily ends up in the [[Living Brain]] before relocating into Spider-Man's body. During this time, Octavius is inspired by the hero's memories to become [[the Superior Spider-Man]] and befriends Midtown High chemistry teacher [[Anna Maria Marconi]]. Eventually, he is persuaded to allow Spider-Man to reclaim control of his body while he returns to his own comatose body once more. After he recovers, Octavius returns to his Doctor Octopus persona and sacrifices himself to stop the [[Vulture (Marvel Comics)|Goblin King]], for which he is hailed as a hero.
* Doctor Octopus appears in ''[[Marvel Super Hero Adventures]]'', voiced by Luc Roderique.<ref name="TVoDO"/>
* Doctor Octopus appears in ''Lego Marvel Spider-Man: Vexed by Venom'', voiced by [[Robbie Daymond]].<ref name="TVoDO" />
* A female incarnation of Doctor Octopus appears in ''[[Spidey and His Amazing Friends]]'',<ref>{{Cite magazine|url=https://ew.com/tv/patrick-stump-marvels-spidey-and-his-amazing-friends-theme-song/|title=Patrick Stump breaks down his theme song for new cartoon Spidey and His Amazing Friends|magazine=[[Entertainment Weekly]]|date=June 7, 2021|access-date=July 12, 2021}}</ref> voiced by Kelly Ohanian.<ref>:{{Cite web|url=https://www.instagram.com/p/CP4ZcAMjEyW/ |archive-url=https://ghostarchive.org/iarchive/s/instagram/CP4ZcAMjEyW |archive-date=December 23, 2021 |url-access=subscription|title=Kelly Ohanian on Instagram|date=June 9, 2021|access-date=July 12, 2021}}{{cbignore}}</ref><ref name="TVoDO" />
* Doctor Octopus appears in ''[[Your Friendly Neighborhood Spider-Man]]'', voiced by [[Hugh Dancy]].<ref>{{Cite web |last=Nolan |first=Liam |date=July 22, 2022 |title=SDCC: Marvel Studios Animation Panel Reveals Future of X-Men '97, What If and Marvel Zombies |url=https://www.cbr.com/marvel-studios-animation-x-men-what-if-zombies-sdcc/ |url-status=live |archive-url=https://web.archive.org/web/20220722185151/https://www.cbr.com/marvel-studios-animation-x-men-what-if-zombies-sdcc/ |archive-date=July 22, 2022 |access-date=July 22, 2022 |website=[[Comic Book Resources]]}}</ref><ref>{{Cite web |last=Hickson |first=Colin |date=2023-10-06 |title=''Spider-Man: Freshman Year'' Synopsis Teases a 'New Era of Spider-Man' |url=https://www.cbr.com/spider-man-freshman-year-synopsis/ |access-date=2024-09-22 |website=CBR |language=en}}</ref><ref name="TVoDO" />

===Film===
{{Main|Otto Octavius (film character)}}
* In an early script for [[The Cannon Group, Inc.|Cannon]]'s aborted Spider-Man film, written by Ted Newsom and [[John Brancato]], Otto Octavius was rewritten to become a teacher and mentor to a college-aged Peter Parker. The cyclotron accident which "creates" Spider-Man also deforms the scientist into Doctor Octopus and results in his mad pursuit of proof of the Fifth Force. "Doc Ock" reconstructs his cyclotron and causes electromagnetic abnormalities, anti-gravity effects, and bi-location, which threatens to engulf New York City and the world. Additionally, [[Bob Hoskins]] and [[Arnold Schwarzenegger]] were considered for the role.<ref name="Leva">{{cite journal| last=Jankiewicz|first=Pat|date=July 2002|title=Scott Leva, the Man Who Was Almost Spider-Man| journal= Starlog/Comics Scene Presents Spider-Man|volume=1|issue=1|pages=62–64}}</ref><ref>{{cite web | url=http://www.ign.com/articles/2000/02/15/review-of-james-camerons-spider-man-scriptment | title=Review of James Cameron's Spider-Man Scriptment | date=February 15, 2000}}</ref><ref>{{Cite web | url=https://books.google.com/books?id=8b4J_Dx6nGQC&dq=james+cameron+spiderman+sandman+boyd&pg=PA5 | title=''Spider-Man'' Films}}</ref><ref>{{cite web | url=https://www.technobuffalo.com/2017/07/15/james-cameron-was-this-close-to-making-a-spider-man-movie/ | title=James Cameron was this close to making a Spider-Man movie | date=July 15, 2017 | access-date=April 2, 2022 | archive-date=June 16, 2018 | archive-url=https://web.archive.org/web/20180616204117/https://www.technobuffalo.com/2017/07/15/james-cameron-was-this-close-to-making-a-spider-man-movie/ | url-status=dead}}</ref><ref>{{Cite web|url=https://thescriptsavant.com/pdf/SpiderMan.pdf|archive-url=https://web.archive.org/web/20211126124928/https://thescriptsavant.com/pdf/SpiderMan.pdf|url-status=dead|title=Spider Man|archive-date=November 26, 2021}}</ref><ref>{{cite web | url=https://www.businessinsider.com/spider-man-movies-never-made-2014-5 | title=6 Spider-Man Movies That Were Never Made | website=[[Business Insider]]}}</ref><ref>{{cite web | url=https://worldoftopics.com/13270-arnold-schwarzenegger-was-supposed-to-play-doctor-octopus.html | archive-url=https://web.archive.org/web/20220416224636/https://worldoftopics.com/13270-arnold-schwarzenegger-was-supposed-to-play-doctor-octopus.html | url-status=usurped | archive-date=April 16, 2022 | title=Arnold Schwarzenegger was supposed to play Doctor Octopus}}</ref><ref>{{cite web | url=https://www.espaciomarvelita.com/2012/12/30/cine/arnold-schwarzenegger-habla-de-spiderman/ | title=Arnold Schwarzenegger habla de Spiderman - Espacio Marvelita | date=December 30, 2012}}</ref>
* Director [[Sam Raimi]] has stated that Doctor Octopus was intended to appear in ''[[Spider-Man (2002 film)|Spider-Man]]'' (2002) and team up with the [[Norman Osborn (2002 film series character)|Green Goblin]], but was not included because Raimi thought it "wouldn't do the movie justice to have a third origin in there".<ref>{{Cite AV media|title = Making The Amazing|type = DVD|publisher = Sony|date = 2004}}</ref>
* Otto Octavius / Doctor Octopus appears in the [[Sony]] film ''[[Spider-Man 2]]'' (2004), portrayed by [[Alfred Molina]].<ref>{{Cite web|last=Aurthur|first=Kate|date=April 16, 2021|title=Alfred Molina Details Doc Ock's Return in 'Spider-Man: No Way Home': 'The Tentacles Do All the Work' (EXCLUSIVE)|url=https://variety.com/2021/film/news/alfred-molina-spider-man-no-way-home-doc-ock-1234953527/|access-date=April 16, 2021|website=Variety|language=en-US}}</ref> This version is a sympathetic, but misguided individual, and the husband and lab partner of Rosie Octavius (portrayed by [[Donna Murphy]]). Initially a well-meaning scientist working with [[Oscorp]] to develop a form of self-sustainable energy to benefit mankind, Octavius turns to villainy after his experiment goes wrong, resulting in Rosie's death and Octavius losing control of his tentacle harness' [[artificial intelligence]], which begins to influence his mind and actions and brings him into conflict with [[Peter Parker (2002 film series character)|Spider-Man]]. With the web-slinger's help, Octavius eventually sees the error of his ways and sacrifices himself to sink a fusion reactor he built into the [[East River]], where he drowns.
** Octavius appears in the [[Marvel Cinematic Universe]] (MCU) film ''[[Spider-Man: No Way Home]]'', portrayed again by Alfred Molina.<ref>{{Cite web |last1=Kit |first1=Borys |last2=Couch |first2=Aaron |date=December 8, 2020 |title='Spider-Man 3': Alfred Molina Returning as Doctor Octopus |url=https://www.hollywoodreporter.com/heat-vision/spider-man-3-alfred-molina-returning-as-doctor-octopus |url-status=live |archive-url=https://web.archive.org/web/20201208184542/https://www.hollywoodreporter.com/heat-vision/spider-man-3-alfred-molina-returning-as-doctor-octopus |archive-date=December 8, 2020 |access-date=August 31, 2021 |website=[[The Hollywood Reporter]]}}</ref><ref name="Molina">{{Cite web|last1=Kit|first1=Borys|last2=Couch|first2=Aaron|date=December 8, 2020|title='Spider-Man 3': Alfred Molina Returning as Doctor Octopus|url=https://www.hollywoodreporter.com/heat-vision/spider-man-3-alfred-molina-returning-as-doctor-octopus|url-status=live|archive-url=https://web.archive.org/web/20201208184542/https://www.hollywoodreporter.com/heat-vision/spider-man-3-alfred-molina-returning-as-doctor-octopus|archive-date=December 8, 2020|access-date=December 8, 2020|website=[[The Hollywood Reporter]]}}</ref> In April 2021, Molina said it was "wonderful" to play the character again. Additionally, he was [[De-aging in film|digitally de-aged]] in the film to resemble how he appeared in 2004, despite his concerns about his fighting style not looking realistic due to his age.<ref name= "OckSurvives">{{Cite web |last=Aurthur |first=Kate |date=April 16, 2021 |title=Alfred Molina Details Doc Ock's Return in 'Spider-Man: No Way Home': 'The Tentacles Do All the Work' (Exclusive) |url=https://variety.com/2021/film/news/alfred-molina-spider-man-no-way-home-doc-ock-1234953527/ |url-status=live |archive-url=https://web.archive.org/web/20210416232314/https://variety.com/2021/film/news/alfred-molina-spider-man-no-way-home-doc-ock-1234953527/ |archive-date=April 16, 2021 |access-date=August 31, 2021 |website=[[Variety (magazine)|Variety]]}}</ref> Prior to his death, Octavius is transported to an alternate universe due to a magic spell gone wrong and receives a cure from an alternate universe version of [[Peter Parker (Marvel Cinematic Universe)|Spider-Man]] before being returned to his native universe.
* {{Anchor|Olivia Octavius}}A female incarnation of Doctor Octopus named '''Dr. Olivia''' "'''Liv'''" '''Octavius''' appears in ''[[Spider-Man: Into the Spider-Verse]]'', voiced by [[Kathryn Hahn]].<ref>{{cite web|url=https://www.ign.com/articles/2018/11/30/spider-man-into-the-spider-verse-official-credits-reveal-surprise-voice-actor-cameos|title=Spider-Man: Into the Spider-Verse Official Credits Reveal Surprise Voice Actor Cameos|last=Vejvoda|first=Jim|website=IGN|date=November 29, 2018|access-date=December 2, 2018|archive-url=https://web.archive.org/web/20181130210649/https://www.ign.com/articles/2018/11/30/spider-man-into-the-spider-verse-official-credits-reveal-surprise-voice-actor-cameos|archive-date=November 30, 2018}}</ref> She is the head scientist of [[Alchemax]] and the [[Kingpin (character)|Kingpin]]'s right-hand woman who sports a large [[Beehive (hairstyle)|beehive hairstyle]], glasses with octagonal lenses, and [[pneumatic]] tentacles tipped with claws. Under the Kingpin's orders, she builds a [[particle accelerator|super-collider]] to access parallel universes. In spite of the initial tests nearly destroying New York City and bringing several [[Alternative versions of Spider-Man|alternate reality versions of Spider-Man]] to their universe, the Kingpin orders Liv to continue working on the collider. She later encounters [[Miles Morales]] and an alternate reality Peter Parker while they are infiltrating Alchemax, but fails to catch them. After confronting the assembled Spider-People at [[Aunt May|May Parker]]'s house alongside the Kingpin and his other henchmen and failing to stop them a second time, Liv tries to stop the heroes at the collider, only to be hit by a truck when the machine goes haywire and melds her universe with aspects of others.
** Additionally, a Doctor Octopus from [[Spider-Woman (Gwen Stacy)|Gwen Stacy]]'s universe makes a non-speaking [[cameo appearance]] in a flashback.{{Citation needed|date=June 2021}}
* Otto Octavius as the Superior Spider-Man and a comic book-accurate Doctor Octopus make non-speaking cameo appearances in ''[[Spider-Man: Across the Spider-Verse]]'' as prisoners of [[Spider-Man 2099]]'s Spider-Society.<ref>{{Cite web |date=2022-12-14 |title=Every Spider-Suit We Spotted in the Across the Spider-Verse Trailer |url=https://gizmodo.com/spider-man-across-the-spider-verse-every-suit-identifie-1849890415 |access-date=2022-12-15 |website=Gizmodo |language=en}}</ref><ref>{{Cite web |last=Luchies |first=Adam |date=May 24, 2023 |title=A Classic 'Spider-Man' Villain Appears in New 'Across the Spider-Verse' TV Spot |url=https://collider.com/spider-man-across-the-spider-verse-tv-spot/ |website=[[Collider (website)|Collider]] |access-date=May 26, 2023}}</ref> Additionally, Liv Octavius appears via archival footage while archival recordings of Alfred Molina are used for other Octavius variants, who make minor appearances.{{Citation needed|date=March 2024}}

===Video games===
====''Spider-Man'' games====
* Doctor Octopus appears in ''[[Questprobe featuring Spider-Man]]''.{{citation needed|date=July 2017}}
* Doctor Octopus appears as a [[boss (video games)|boss]] in ''[[The Amazing Spider-Man (handheld video game)|The Amazing Spider-Man]]'' (1990).{{citation needed|date=July 2017}}
* Doctor Octopus appears in ''[[Spider-Man: The Video Game]]''.{{citation needed|date=July 2017}}
* Doctor Octopus appears as the final boss of ''[[Spider-Man: Return of the Sinister Six]]'' (1992).{{citation needed|date=July 2017}} This version is the leader of the [[Sinister Six|titular team]].
* Doctor Octopus appears as a boss in ''[[Spider-Man vs. The Kingpin]]''.{{citation needed|date=July 2017}}
* Doctor Octopus appears as a boss in ''[[Spider-Man (1995 video game)|Spider-Man]]'' (1995).{{citation needed|date=July 2017}}
* Doctor Octopus appear in ''Spider-Man: The Sinister Six'', voiced by Ken Roberts.<ref name="TVoDO" />
* Doctor Octopus appears as a boss in ''[[Spider-Man: Lethal Foes]]''.{{citation needed|date=July 2017}}
* Doctor Octopus appears as a boss in ''[[Spider-Man (2000 video game)|Spider-Man]]'' (2000), voiced again by Efrem Zimbalist Jr.<ref name="TVoDO" /> While pretending to have reformed, he works with [[Cletus Kasady|Carnage]] to turn everyone in New York into [[Symbiote (comics)|symbiotes]], but they are both defeated by Spider-Man. Following this, the [[Carnage (comics)|Carnage symbiote]] bonds with Doctor Octopus, turning him into '''Monster-Ock''' (voiced by Marcus Shirock).<ref name="TVoDO" /> After Monster-Ock is defeated, Doctor Octopus is returned to normal and promptly arrested.
* Doctor Octopus appears as the final boss of ''[[Spider-Man 2: The Sinister Six]]''.{{citation needed|date=July 2017}} This version is a member of the Sinister Six.
* Doctor Octopus makes a [[cameo appearance]] in ''[[Spider-Man 2: Enter Electro]]''.{{citation needed|date=July 2017}}
* Doctor Octopus appears as the final boss of the ''[[Spider-Man 2 (2004 video game)|Spider-Man 2]]'' film tie-in game, voiced by Alfred Molina.<ref name="TVoDO" />
* Doctor Octopus appears as a boss and playable character in ''[[Spider-Man: Friend or Foe]]'', voiced by [[Joe Alaskey]].<ref name="TVoDO" /> He and several supervillains attack Spider-Man until they are all attacked by P.H.A.N.T.O.M.s under [[Mysterio]]'s command. Doc Ock is captured along with the other villains, placed under mind control, and sent to [[Tokyo]] to retrieve a meteor shard located there. After Spider-Man defeats Doctor Octopus and destroys the mind-control device, the latter joins forces with the former to exact revenge on Mysterio.
* Otto Octavius appears in ''[[Spider-Man: Edge of Time]]'', voiced by [[Dave B. Mitchell]].<ref name="TVoDO" /> [[Alchemax]] scientist Walker Sloan travels back from the year [[Marvel 2099|2099]] to establish his company in the 1970s, saving Octavius from the accident that would have fused his tentacle harness to him and recruiting him in the process. Despite having never turned to crime, Octavius still uses his tentacles as research tools. The pair attempt to use a mind-controlled [[Eddie Brock|Anti-Venom]] to kill Spider-Man, but when [[Spider-Man 2099]] intervenes, Doctor Octopus, Sloan, and Anti-Venom are all accidentally thrown into Sloan's time portal and end up fused into the monstrous '''Atrocity''' (voiced by [[Fred Tatasciore]]) equipped with Doctor Octopus' tentacles and Anti-Venom's ability to negate the present day Spider-Man's powers. Spider-Man eventually defeats Atrocity, throwing it back into the time portal, before he and Spider-Man 2099 undo Sloan's changes, restoring history.
* Multiple alternate reality versions of Doctor Octopus appear as bosses in ''[[Spider-Man Unlimited (video game)|Spider-Man Unlimited]]'', voiced by [[Kyle Hebert]].<ref name="TVoDO" /> They are members of a multiversal Sinister Six. Additionally, Octavius as the Superior Spider-Man, Superior Venom, and Superior Octopus appear as playable characters.<ref>{{cite web|url=https://news.marvel.com/games/83811/five-new-spider-verse-characters-just-joined-roster-spider-man-unlimited/|title=Five New Spider-Verse Characters Just Joined the Roster of 'Spider-Man Unlimited'|website=News - Marvel.com}}</ref>

==== ''Marvel's Spider-Man'' series ====
Otto Octavius appears in [[Insomniac Games]]' ''[[Spider-Man (Insomniac Games series)|Marvel's Spider-Man]]'' series, voiced by [[William Salyers]].<ref>{{cite web |url=https://screenrant.com/spider-man-ps4-ending-explained/ |title=Marvel's Spider-Man PS4 Ending Explained |last=Mithaiwala |first=Mansoor |date=September 6, 2018 |website=[[Screen Rant]] |publisher=Valnet Inc. |access-date=September 7, 2018}}</ref><ref name="TVoDO" /> Once a close friend of [[Norman Osborn]] and co-founder of Oscorp, this version left the company due to its unethical genetic experiments. Founding his own company, Octavius Industries, he worked to perfect prosthetic limb technology, motivated by a neurological disorder he was developing. Octavius later employed [[Peter Parker (Insomniac Games character)|Peter Parker]], whom he mentored, as his lab assistant and eventually became aware of his activities as Spider-Man, but chose to hide this from him.
* First appearing as the final boss of ''[[Spider-Man (2018 video game)|Marvel's Spider-Man]]'' (2018), Octavius gains support from [[Advanced Idea Mechanics|A.I.M.]] after Norman exploits his position as mayor to remove Octavius' grant funding in an attempt to persuade him to return to Oscorp. During this time, Octavius befriends [[Mister Negative|Martin Li]], a victim of Oscorp's experimentation who has been leading terrorist attacks against the city to destroy Norman, inspiring Octavius to pursue his own vendetta against his former friend. While working on a set of mechanical thought-controlled tentacles with Parker, Octavius loses control of his emotions due to a defect with the neural implant used to connect them directly to his nervous system and causes a mass prison break from [[Ryker's Island]] and the [[Raft (comics)|Raft]]. Forming the [[Sinister Six]] with Li and several of Spider-Man's foes, Octavius, now going by "Doctor Octopus", organizes a series of attacks on Oscorp-owned properties and releases their Devil's Breath virus on New York in the hopes of exposing Norman's crimes. After capturing and nearly killing Norman, Octavius is confronted by Parker as Spider-Man, who rescues Norman and battles Octavius atop Oscorp tower, during which the latter reveals his knowledge of Parker's double life. Following his defeat, Octavius pleads for help, claiming the tentacles' artificial intelligence was in control of his actions, but a heartbroken Parker leaves him to face justice for his crimes, leading to Octavius' imprisonment at the Raft and Octavius Industries being shut down.
* Octavius makes a cameo appearance in a flashback depicted in ''[[Spider-Man: Miles Morales]]''.<ref>{{cite web | url=https://screenrant.com/spider-man-miles-morales-doctor-octopus-cameo-explained/ | title=Spider-Man: Miles Morales' Doctor Octopus Cameo Explained | website=[[Screen Rant]] | date=November 21, 2020}}</ref>
* Octavius makes a cameo appearance in the mid-credits scene of ''[[Marvel's Spider-Man 2]]'' (2023).<ref>{{cite web | url=https://www.ign.com/articles/spider-man-2-ending-explained-insomniac-sequel-green-goblin-silk | title=Spider-Man 2 Ending Explained: How Insomniac Sets up the Next Sequel | date=October 19, 2023}}</ref> Following the events of the main story, Norman visits his cell at the Raft to inquire about the Spider-Men's secret identities. Octavius taunts him with the belief that he needed to experience loss as he had while making preparations for the "final chapter".<ref>{{Cite web |last=Schedeen |first=Jesse |date=2023-10-19 |title=Spider-Man 2 Ending Explained: How Insomniac Sets Up the Next Sequel - IGN |url=https://www.ign.com/articles/spider-man-2-ending-explained-insomniac-sequel-green-goblin-silk |access-date=2023-10-19}}</ref> Additionally, the Superior Spider-Man's suit appears as an alternate skin for Peter.<ref>{{cite video game|title=[[Spider-Man 2]]|developer=[[Insomniac Games]] |publisher=[[Sony Interactive Entertainment]]|date=2023}}</ref>

====Other games====
* Doctor Octopus appears in ''[[LittleBigPlanet]]'' via the "Marvel Costume Kit 1" [[downloadable content|DLC]].<ref name="LittleBigPlanetMCK13">{{cite web|title=Marvel Costume Kit 1|url=http://www.littlebigplanet.com/en/downloadable_content_items/1105?t=US|url-status=dead|archive-url=https://web.archive.org/web/20130219210912/http://littlebigplanet.com/en/downloadable_content_items/1105?t=US|archive-date=February 19, 2013|access-date=December 30, 2012|publisher=[[Sony]]}}</ref>
* Doctor Octopus appears in ''[[Marvel Super Hero Squad Online]]'', voiced initially by [[Charlie Adler]],<ref>{{cite web|last1=Minn|first1=Jay|title=Marvel Super Hero Squad Online|url=https://www.imdb.com/title/tt1971469/|access-date=February 11, 2016|website=IMDb|date=April 29, 2011}}</ref> and later by Tom Kenny.<ref name="TVoDO" />
* Doctor Octopus appears as a support card in ''[[Ultimate Marvel vs. Capcom 3]]''{{'}}s "Heroes and Heralds Mode". Producer Ryota Niitsuma confirmed that Doctor Octopus was planned to be a playable character at one point during production, with character art and a theme song being developed for him, before the decision was made to cut him from the roster.<ref>{{cite news|last1=Taylor|first1=Nicholas|title=Doc Ock even had his theme song completed for MvC3? Niitsuma confirms that this Spidey villain's development had gone further than previously thought|url=https://www.eventhubs.com/news/2016/dec/27/doc-ock-even-had-his-theme-song-completed-mvc3-niitsuma-confirms-spidey-villains-development-had-gone-further-previously-thought/|newspaper=Eventhubs|date=December 27, 2016}}</ref>
* Doctor Octopus appears as a boss in ''[[Marvel: Avengers Alliance]]''. This version is a member of the Sinister Six. Additionally, an alternate reality version who became the Superior Spider-Man appears as a playable character.{{citation needed|date=February 2016}}
* Doctor Octopus appears as a boss in ''[[Marvel Heroes (video game)|Marvel Heroes]]'', voiced again by Tom Kenny.<ref name="TVoDO" /> Additionally, the Superior Spider-Man appears as a playable character.
* Two incarnations of Doctor Octopus appear as playable characters in ''[[Marvel Puzzle Quest]]''.<ref>{{cite web|title=Piecing Together Marvel Puzzle Quest: Doctor Octopus|url=https://news.marvel.com/games/66023/piecing-together-marvel-puzzle-quest-doctor-octopus/|website=News - Marvel.com}}</ref>
* Doctor Octopus appears as a playable character and boss in ''[[Lego Marvel Super Heroes]]'', voiced by [[Dee Bradley Baker]].<ref>{{cite web|title=LEGO Marvel Superheroes: Stan Lee Hulks Out - Comic-Con 2013 - IGN Video|date=July 20, 2013 |url=http://www.ign.com/videos/2013/07/20/lego-marvel-superheroes-stan-lee-hulks-out-comic-con-2013}}</ref> Additionally, the ''[[Ultimate Spider-Man (TV series)|Ultimate Spider-Man]]'' TV series incarnation and Octavius as the Superior Spider-Man appear as playable characters.<ref>{{cite tweet|user=LEGOMarvelGame|author=LEGO Marvel Super Heroes 2|number=389075434740019200|date=October 12, 2013|title=Your first look at Superior Spider-Man! #MarvelGames #LEGOMarvel #LEGOMarvelNYCC}}/photo/1</ref>
* Doctor Octopus make a cameo appearance in ''[[Disney Infinity 2.0]]'',<ref>{{cite web|date=June 10, 2014|title=Spider-Man, Venom and More Added to "Disney Infinity: Marvel Super Heroes"|work=Comic Book Resources |url=http://www.comicbookresources.com/?page=article&id=53340}}</ref> voiced again by Tom Kenny.<ref name="TVoDO" />
* Doctor Octopus appears in ''[[Marvel: Contest of Champions]]'' as a member of the Sinister Six.<ref>{{cite web|title=Entering Marvel Contest of Champions: Doctor Octopus|url=https://news.marvel.com/games/71967/entering-marvel-contest-champions-doctor-octopus/|website=News - Marvel.com}}</ref>
* Doctor Octopus appears as a playable character and boss in ''[[Marvel: Future Fight]]''.<ref name="TVoDO" /> Additionally, the Superior Spider-Man appears as an alternate costume.
* Doctor Octopus appears as a boss in ''[[Marvel: Avengers Alliance#Marvel: Avengers Alliance 2|Marvel: Avengers Alliance 2]]''.<ref>{{Cite web|title=Doctor Octopus &#124; Marvel: Avengers Alliance 2|url=https://marvelavengersalliance2.com/aa2_characters/doctor-octopus/|url-status=dead|archive-url=https://web.archive.org/web/20160419083438/https://marvelavengersalliance2.com/aa2_characters/doctor-octopus/|archive-date=April 19, 2016|access-date=April 5, 2016}}</ref>
* Doctor Octopus appears as a boss and playable character in ''[[Lego Marvel Super Heroes 2]]''.<ref>{{cite web|title=Characters|url=http://www.ign.com/wikis/lego-marvel-super-heroes-2/Characters|access-date=February 14, 2018|website=IGN Database|date=May 19, 2017}}</ref> Additionally, the Superior Spider-Man appears as a playable character.
* Doctor Octopus appears in ''[[Marvel Strike Force]]'' as a member of the Sinister Six.{{citation needed|date=March 2023}}
* Doctor Octopus appears as a boss in ''[[Marvel Ultimate Alliance 3: The Black Order]]'', voiced again by William Salyers.<ref name="TVoDO" /> This version serves as second-in-command of the Sinister Six, led by the Green Goblin.<ref>{{Cite web|url=https://www.ign.com/wikis/marvel-ultimate-alliance-3/Chapter_2_-_The_Raft_Walkthrough|title=Chapter 2 - The Raft Walkthrough|date=August 6, 2019|accessdate=June 17, 2021|website=IGN Database}}</ref><ref>{{Cite web|url=https://www.imdb.com/title/tt9445030/|title=Marvel Ultimate Alliance 3: The Black Order|date=June 19, 2019|accessdate=June 17, 2021|website=IMDb.com}}</ref>

===Miscellaneous===
[[File:Spider-Man, Octo-Girl volume 1 cover.jpg|thumb|right|Cover of ''Spider-Man: Octopus-Girl'' Vol. 1.]]
* Doctor Octopus appears in ''[[The Amazing Adventures of Spider-Man]]'', voiced by [[Rodger Bumpass]].{{Citation needed|date=April 2011}} This version is the leader of the [[Sinister Syndicate]].
* Doctor Octopus appears in ''[[Marvel Universe: LIVE!]]'' as a member of the Sinister Six.<ref>{{cite web|url=http://marvel.com/news/story/21561/character_reveals_for_marvel_universe_live|title=Doctor Strange Enters the Infinity Wars|website=News - Marvel.com}}</ref>
* Doctor Octopus appears in the ''[[Spider-Verse (franchise)|Spider-Verse]]'' manga ''[[Spider-Man: Octo-Girl]]'', in which he ends up in the body of Japanese middle schooler '''Otoha Okutamiya'''.<ref name="manga spinoff">{{Cite web |last=Pineda |first=Rafael Antonio |date=May 30, 2023 |title=''Spider-Man: Across the Spider-Verse'' Film Gets Manga Spinoff About Doc Ock in Schoolgirl's Body |url=https://www.animenewsnetwork.com/news/2023-05-29/spider-man-across-the-spider-verse-film-gets-manga-spinoff-about-doc-ock-in-schoolgirl-body/.198587 |url-status=live |archive-url=https://web.archive.org/web/20230530020904/https://www.animenewsnetwork.com/news/2023-05-29/spider-man-across-the-spider-verse-film-gets-manga-spinoff-about-doc-ock-in-schoolgirl-body/.198587 |archive-date=May 30, 2023 |access-date=May 30, 2023 |website=[[Anime News Network]]}}</ref><ref>{{cite comic |title=Spider-Man: Octopus Girl |writer=Furuhashi, Hideyuki |artist=Court, Betten |date=June 20, 2023 |volume=1 |issue=1 |publisher=[[Shōnen Jump+]]}}</ref>

===Merchandise===
* Doctor Octopus received a figure in [[Mattel]]'s "[[Secret Wars (toy line)|Secret Wars]]" line.
* Doctor Octopus received several figures in [[Toy Biz]]'s Spider-Man and [[Marvel Legends]] series.
* Doctor Octopus received a figure in [[Hasbro]]'s Spider-Man: Origin series.
* Alfred Molina's incarnation of Doctor Octopus received a figure in Hasbro's Marvel Legends: Spider-Man line.
* ''The Spectacular Spider-Man'' incarnation of Doctor Octopus received a figure from Hasbro.
* Doctor Octopus received a figure in the Marvel Manga Twist'ems line.
* Doctor Octopus received several statues and mini-busts from [[Diamond Select Toys]], [[Art Asylum]] and [[Bowen Designs]].
* Doctor Octopus received a figurine in [[The Classic Marvel Figurine Collection]].