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Multiple sclerosis
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=== Medications === Medications that influence voltage-gated sodium ion channels are under investigation as a potential neuroprotective strategy because of hypothesized role of sodium in the pathological process leading to axonal injury and accumulating disability. There is insufficient evidence of an effect of sodium channel blockers for people with MS.<ref>{{cite journal | vauthors = Yang C, Hao Z, Zhang L, Zeng L, Wen J | title = Sodium channel blockers for neuroprotection in multiple sclerosis | journal = The Cochrane Database of Systematic Reviews | issue = 10 | pages = CD010422 | date = October 2015 | volume = 2015 | pmid = 26486929 | doi = 10.1002/14651858.CD010422.pub2 | pmc = 9242538 }}</ref>
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