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2C-B
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===Duration=== When [[Oral administration|orally]] consumed, 2C-B has a much longer delay before the onset of effects than when it is insufflated. Oral ingestion generally takes roughly 45β75 minutes for the effects to be felt, plateau lasts 2β4 hours, and coming down lasts 1β2 hours. [[Rectal administration]] onset varies from 5 to 20 minutes. Insufflated onset takes 1β10 minutes for effects to be felt. The duration can last from 4 to 12 hours depending on route of administration, dose, and other factors.<ref name="erowid effects"/> With insufflation, the effects are more abrupt and intense but have a significantly shorter duration, while oral usage results in a milder, longer experience. When insufflated, the onset happens very rapidly, usually reaching the peak at about 20β40 minutes and plateauing for 2β3 hours. 2C-B is also considered one of the most painful drugs to insufflate, with users reporting intense nasal burning.<ref name="erowid basics"/> The sudden intensity of the experience combined with the pain can often start the experience with a negative imprint and nausea is also increased with insufflation, compounding the issue.
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