Editing AMPA receptor (section)

==== Desensitization Mechanism ====
The mechanism of desensitization is due to a small change in angle of one of the parts of the binding site, closing the pore.<ref>{{cite journal | vauthors = Armstrong N, Jasti J, Beich-Frandsen M, Gouaux E | title = Measurement of conformational changes accompanying desensitization in an ionotropic glutamate receptor | journal = Cell | volume = 127 | issue = 1 | pages = 85–97 | date = October 2006 | pmid = 17018279 | doi = 10.1016/j.cell.2006.08.037 | s2cid = 16564029 | doi-access = free }}</ref>  AMPARs open and close quickly (1ms), and are thus responsible for most of the fast excitatory [[Synaptic transmission|postsynaptic transmission]] in the central nervous system.<ref name="Platt2007" />