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Adipocyte
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==Development== [[File:Lipoblast features, annotated.png|thumb|[[Lipoblast]] features on [[histology]], [[H&E stain]].]] '''Pre-adipocytes''' are undifferentiated [[fibroblast]]s that can be stimulated to form adipocytes. Studies have shed light into potential molecular mechanisms in the fate determination of pre-adipocytes although the exact lineage of adipocyte is still unclear.<ref name="Coskun_2010">{{cite journal | vauthors = Coskun H, Summerfield TL, Kniss DA, Friedman A | title = Mathematical modeling of preadipocyte fate determination | journal = Journal of Theoretical Biology | volume = 265 | issue = 1 | pages = 87β94 | date = July 2010 | pmid = 20385145 | doi = 10.1016/j.jtbi.2010.03.047 | bibcode = 2010JThBi.265...87C }} *{{lay source |template=cite news |date=August 18, 2010 |title=Scientists closer to finding what causes the birth of a fat cell |url=https://www.sciencedaily.com/releases/2010/08/100816114835.htm |work=ScienceDaily}}</ref><ref name="coskun2010">{{cite journal | vauthors = Coskun H, Summerfield TL, Kniss DA, Friedman A | title = Mathematical modeling of preadipocyte fate determination | journal = Journal of Theoretical Biology | volume = 265 | issue = 1 | pages = 87β94 | date = July 2010 | pmid = 20385145 | doi = 10.1016/j.jtbi.2010.03.047 | bibcode = 2010JThBi.265...87C }}</ref> The variation of body fat distribution resulting from normal growth is influenced by nutritional and hormonal status dependent on intrinsic differences in cells found in each adipose depot.<ref name="pmid26054752">{{cite journal | vauthors = Fried SK, Lee MJ, Karastergiou K | title = Shaping fat distribution: New insights into the molecular determinants of depot- and sex-dependent adipose biology | journal = Obesity | volume = 23 | issue = 7 | pages = 1345β1352 | date = July 2015 | pmid = 26054752 | pmc = 4687449 | doi = 10.1002/oby.21133 | type = Review }}</ref> [[Mesenchymal stem cell]]s can differentiate into adipocytes, [[connective tissue]], muscle or [[bone]].<ref name="Birbrair 2298β2314"/> The precursor of the adult cell is termed a [[lipoblast]], and a tumor of this cell type is known as a [[lipoblastoma]].<ref name="pmid18528880">{{cite journal | vauthors = Hong R, Choi DY, Do NY, Lim SC | title = Fine-needle aspiration cytology of a lipoblastoma: a case report | journal = Diagnostic Cytopathology | volume = 36 | issue = 7 | pages = 508β511 | date = July 2008 | pmid = 18528880 | doi = 10.1002/dc.20826 | s2cid = 22668394 }}</ref>
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