Editing Arthrogryposis (section)

===Molecular basis===
Research has shown that there are more than 35 specific genetic disorders associated with arthrogryposis. Most of those [[mutations]] are [[missense]], which means the mutation results in a different [[amino acid]]. Other mutations that could cause arthrogryposis are: single gene defects (X-linked recessive, autosomal recessive and autosomal dominant), [[mitochondrial]] defects and [[chromosomal]] disorders (for example: [[trisomy 18]]).<ref name=Bevan /> This is mostly seen in distal arthrogryposis. Mutations in at least five genes (TNN12, TNNT3, TPM2, MYH3 and MYH8) could cause distal arthrogryposis.<ref name=Bamshad /> There could be also connective tissue, neurological or muscle development disorders.<ref name=Bamshad />