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Bone tumor
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==Diagnosis== A bone tumour may be felt on examination, following which a [[Projectional radiography|plain X-ray]] is usually carried out.<ref name=Maruth2018/><ref name="CostelloeMadewell2013">{{cite journal | vauthors = Costelloe CM, Madewell JE | title = Radiography in the initial diagnosis of primary bone tumors | journal = AJR. American Journal of Roentgenology | volume = 200 | issue = 1 | pages = 3β7 | date = January 2013 | pmid = 23255735 | doi = 10.2214/AJR.12.8488 }}</ref> Blood tests might include a [[complete blood count]], inflammatory markers, [[Gel electrophoresis of proteins|serum electrophoresis]], [[Prostate-specific antigen|PSA]], [[kidney function]] and [[liver function]].<ref name=Maruth2018/> Urine may be sent for [[Bence Jones protein]].<ref name=Maruth2018/> Other [[Radiography| tests]] that might be requested include a [[CT scan]], [[MRI]], [[Positron emission tomography|PET scan]] and [[bone scintigraphy]]. For confirmation of diagnosis, a [[biopsy]] for [[Histopathology|histological evaluation]] might be required, using either a needle or by incision (open biopsy).<ref name=Maruth2018/><ref name="orthoinfo"/> ===Staging=== <gallery> File:Diagram showing stage 1A bone cancer CRUK 198.svg|Stage 1A bone cancer File:Diagram showing stage 1B bone cancer CRUK 201.svg|Stage 1B bone cancer File:Diagram showing stage 2A bone cancer CRUK 211.svg|Stage 2A bone cancer File:Diagram showing stage 2B bone cancer CRUK 215.svg|Stage 2B bone cancer File:Diagram showing stage 3 bone cancer CRUK 218.svg|Stage 3 bone cancer </gallery>
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