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CADASIL
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== Society and culture == [[John Ruskin]] has been suggested to have had CADASIL.<ref name="Kempster">{{cite journal |vauthors=Kempster PA, Alty JE |title=John Ruskin's relapsing encephalopathy |journal=Brain |volume=131 |issue=Pt 9 |pages=2520β5 |date=September 2008 |pmid=18287121 |doi=10.1093/brain/awn019 |doi-access= }}</ref> Ruskin reported in his diaries having visual disturbances consistent with the disease and it has also been suggested that it might have been a factor in causing him to describe [[James Whistler]]'s ''[[Nocturne in Black and Gold β The Falling Rocket]]'' as "ask[ing] two hundred guineas for throwing a pot of paint in the public's face". This resulted in the famous libel trial that resulted in a jury's awarding Whistler one farthing damages.<ref name="Kempster"/> Recent research into the illness of philosopher [[Friedrich Nietzsche]] has suggested that his mental illness and death may have been caused by CADASIL rather than tertiary syphilis.<ref>{{cite journal |vauthors=Hemelsoet D, Hemelsoet K, Devreese D |title=The neurological illness of Friedrich Nietzsche |journal=Acta Neurol Belg |volume=108 |issue=1 |pages=9β16 |date=March 2008 |pmid=18575181 }}</ref> Likewise, the early death of the composer [[Felix Mendelssohn]], at age 37, from a stroke has been potentially linked to CADASIL. His sister, [[Fanny Mendelssohn]], was similarly affected.<ref>{{Cite web|url=https://accounts.google.com/v3/signin/identifier?dsh=S-1525686783%3A1658789663940002&continue=https%3A%2F%2Fwww.blogger.com%2Fblogin.g%3FblogspotURL%3Dhttp%3A%2F%2Fchambermusictoday.blogspot.com%2F2008%2F09%2Fmendelssohns-premature-death.html%26type%3Dblog%26zx%3D17zq5140evif8&hl=en-US&passive=true&service=blogger&flowName=WebLiteSignIn&flowEntry=ServiceLogin&ifkv=AQN2RmX5L8KsTIEzM1Pj-xbyDV30BvMW4IAPJXiUgDWWJGRPaPYIhBhJLk6SFadxRplVl5hCwqSvVA|title=Blogger|website=accounts.google.com}}</ref> And [[James Dewar (musician)|James Dewar]], best known as vocalist for [[Robin Trower]], died age 59 from complications of CADASIL.<ref>{{cite web |title=Jimmy Dewar, singer/bassist for Robin Trower's Rock Sensation |url=https://rockandrollparadise.com/jimmy-dewar-5-2002/ |website=Rock and Roll Paradise |access-date=2 July 2021 |date=23 March 2019}}</ref> In the movie ''[[The Sea Inside]]'', one of the characters is stated to have CADASIL.<ref>{{cite web |last1=Fisher |first1=Christopher |title=CADASIL, A Vascular Brain Disorder, Is Often Misdiagnosed As Multiple Sclerosis |url=https://www.bmedreport.com/archives/24709 |website=BMED Report |access-date=28 July 2021 |date=14 March 2011}}</ref> In the [[Netflix]] 2023 limited series ''[[The Fall of the House of Usher (miniseries)|The Fall of the House of Usher]]'', the main character [[Roderick Usher]] suffers from this disorder and much of the series storyline surrounds his criminal and illicit attempts to find a cure. The limited series is based on the [[Edgar Allan Poe bibliography|life's work]] of [[Edgar Allan Poe]].
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