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Calcium phosphate
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==Clinical significance== Calcium phosphate stones account for approximately 15% of [[kidney stone disease]]. Calcium phosphate stones tend to grow in alkaline urine, especially when [[Proteus (bacterium)|''Proteus'' bacteria]] are present. It is the most common type in pregnant women.<ref name=Frassetto2011>{{cite journal| author=Frassetto L, Kohlstadt I| title=Treatment and prevention of kidney stones: an update. | journal=Am Fam Physician | year= 2011 | volume= 84 | issue= 11 | pages= 1234β42 | pmid=22150656 | doi= | pmc= | url=https://pubmed.ncbi.nlm.nih.gov/22150656 }}</ref> Calcium phosphate is the usual constitution of [[microcalcification]]s of the [[breast]], particularly [[dystrophic calcification]]s. Microcalcifications as can be seen on [[mammography]] can be an early sign of [[breast cancer]]. Based on morphology, it is possible to classify by radiography how likely microcalcifications are to indicate cancer.<ref>{{cite journal |last1=Nalawade |first1=Yojana V |title=Evaluation of breast calcifications |journal=The Indian Journal of Radiology & Imaging |date=November 2009 |volume=19 |issue=4 |pages=282β286 |doi=10.4103/0971-3026.57208 |pmid=19881103 |issn=0971-3026|pmc=2797739 |doi-access=free }}</ref> <gallery heights=160 widths=200> File:Urine crystals comparison.png|Urine crystals comparison, with calcium phosphate crystal depicted at top center. File:Histopathology of dystrophic microcalcifications in ductal carcinoma in situ.jpg|Histopathology of dystrophic calcium phosphate microcalcifications in [[ductal carcinoma in situ]] (DCIS) of the breast, H&E stain. </gallery>
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