Editing Calorie restriction (section)

===Humans===
Decreasing [[Food energy#Recommended daily intake|caloric intake]] by 20-30%, while fulfilling nutrient requirements, has been found to remedy diseases of aging, including cancer, cardiovascular disease, dementia, and diabetes in humans, and result in an average loss of {{convert|7.9|kg|lbs}} in body weight, but because of the long lifespan of humans, evidence that calorie restriction could prevent age-related disease in humans remains under preliminary research.<ref name=lee/><ref>{{Cite journal |display-authors=6 |vauthors=Caristia S, Vito M, Sarro A, Leone A, Pecere A, Zibetti A, Filigheddu N, Zeppegno P, Prodam F, Faggiano F, Marzullo P |date=July 2020 |title=Is Caloric Restriction Associated with Better Healthy Aging Outcomes? A Systematic Review and Meta-Analysis of Randomized Controlled Trials |journal=Nutrients |volume=12 |issue=8 |page=2290 |doi=10.3390/nu12082290 |pmc=7468870 |pmid=32751664 |doi-access=free}}</ref> While calorie restriction leads to weight and fat loss, the precise amount of calorie intake and associated fat mass for optimal health in humans is not known.<ref name=lee/> Moderate amounts of calorie restriction may have harmful effects on certain population groups, such as lean people with low body fat.<ref name=lee/>