Editing Chondrosarcoma (section)

==Treatment==
Treatment depends on the location of the disease and the aggressiveness of the tumors.<ref name="urlChondrosarcoma : Cancerbackup">{{cite web |url=http://www.cancerbacup.org.uk/Cancertype/Bone/Typesofbonecancer/Chondrosarcoma#3340 |title=Chondrosarcoma : Cancerbackup |access-date=2009-02-14 |archive-url=https://web.archive.org/web/20080905213942/http://www.cancerbacup.org.uk/Cancertype/Bone/Typesofbonecancer/Chondrosarcoma#3340 |archive-date=2008-09-05 |url-status=dead }}</ref>  

Surgery is the main form of treatment for chondrosarcoma.  Musculoskeletal tumor specialists or orthopedic oncologists are usually chosen to treat chondrosarcoma, unless it is located in the skull, spine, or chest cavity, in which case, a neurosurgeon or thoracic surgeon experienced with sarcomas is chosen.  Often, a [[limb-sparing techniques|limb-sparing operation]] can be performed, but in some cases amputation is unavoidable.  Amputation of the [[arm]], [[leg]], [[jaw]], or half of the [[pelvis]] (called a [[hemipelvectomy]]) may be necessary in some cases.{{cn|date=October 2020}}

There are two kinds of hemipelvectomy – internal and external.
*  External hemipelvectomy – is removal of that half of the pelvis with the amputation of the leg.   It is also called hindquarter amputation.
*  Internal hemipelvectomy – is removal of that half of the pelvis,  but the leg is left intact.

Amputation at the hip is called hip disarticulation and amputees who have had this amputation are also called hip disartics.

Chemotherapy or traditional radiotherapy are not very effective for most chondrosarcomas, although [[proton therapy]] is showing promise with local tumor control at over 80%.<ref name="urlProton Therapy at PSI (Protonentherapie)">{{cite web |url=http://p-therapie.web.psi.ch/e/klinikerfahrung.html |title=Proton Therapy at PSI (Protonentherapie) |access-date=2009-02-14}}</ref>

Complete surgical ablation is the most effective treatment, but sometimes this is difficult. [[Proton therapy]] radiation can be useful in awkward locations to make surgery more effective.

Recent studies have shown that induction of [[apoptosis]] in high-grade chondrosarcoma, both directly and by enhancement of response to [[chemotherapy]] and [[radiation]], is a valid therapeutic strategy.<ref name="JamilHowie">Jamil N, Howie S, Salter DM. Therapeutic molecular targets in human chondrosarcoma .Int J Exp Pathol 2010; 91:387–93</ref>