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Chromosomal inversion
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==Nomenclature== [[File:Three chromosomal abnormalities with ISCN nomenclature.png|thumb|330px|Three chromosomal abnormalities with ISCN nomenclature, with increasing complexity: '''(A)''' A tumour karyotype in a male with loss of the Y chromosome, '''(B)''' Prader–Willi Syndrome i.e. deletion in the 15q11-q12 region and '''(C)''' an arbitrary karyotype that involves a variety of autosomal and allosomal abnormalities including inversions (abbreviated as ''inv'').<ref>{{cite journal | vauthors = Warrender JD, Moorman AV, Lord P | title = A fully computational and reasonable representation for karyotypes | journal = Bioinformatics | volume = 35 | issue = 24 | pages = 5264–5270 | date = December 2019 | pmid = 31228194 | pmc = 6954653 | doi = 10.1093/bioinformatics/btz440 }}<br />- "This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ {{Webarchive|url=https://web.archive.org/web/20151121114042/http://creativecommons.org/licenses/by/4.0/ |date=2015-11-21 }})"</ref>]] [[File:Human karyotype with bands and sub-bands.png|thumb|300px|Human [[karyotype]] with annotated bands and sub-bands as used for the nomenclature of chromosome abnormalities. It shows dark and white regions as seen on [[G banding]]. Each row is vertically aligned at [[centromere]] level. It shows 22 [[Homologous chromosome|homologous]] [[autosomal]] chromosome pairs as well as both the female (XX) and male (XY) versions of the two [[sex chromosome]]s. {{further|Karyotype}}]] The [[International System for Human Cytogenomic Nomenclature]] (ISCN) is an international standard for [[human chromosome]] [[nomenclature]], which includes band names, symbols, and abbreviated terms used in the description of human chromosome and chromosome abnormalities. Abbreviations include ''inv'' for inversions.<ref>{{cite web|url=https://www.coriell.org/0/sections/support/global/iscn_help.aspx?PgId=263|title=ISCN Symbols and Abbreviated Terms|website=Coriell Institute for Medical Research|access-date=2022-10-27|archive-date=2022-10-27|archive-url=https://web.archive.org/web/20221027143728/https://www.coriell.org/0/Sections/Support/Global/iscn_help.aspx?PgId=263|url-status=live}}</ref>
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