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DNA methylation
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=== Genome expansion === DNA methylation of transposable elements has been known to be related to genome expansion. However, the evolutionary driver for genome expansion remains unknown. There is a clear correlation between the size of the genome and CpG, suggesting that the DNA methylation of transposable elements led to a noticeable increase in the mass of DNA.<ref>{{cite journal | vauthors = Zhou W, Liang G, Molloy PL, Jones PA | title = DNA methylation enables transposable element-driven genome expansion | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 117 | issue = 32 | pages = 19359β19366 | date = August 2020 | pmid = 32719115 | pmc = 7431005 | doi = 10.1073/pnas.1921719117 | doi-access = free | bibcode = 2020PNAS..11719359Z }}</ref>
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