Editing Drug overdose (section)

==Diagnosis==
The substance that has been taken may often be determined by asking the person. However, if they will not, or cannot, due to an [[altered level of consciousness]], provide this information, a search of the home or questioning of friends and family may be helpful.

Examination for [[toxidrome]]s, drug testing, or laboratory test may be helpful. Other laboratory test such as [[glucose]], [[urea]] and [[electrolyte]]s, [[paracetamol]] levels and [[salicylate]] levels are typically done. Negative drug-drug interactions have sometimes been misdiagnosed as an acute drug overdose, occasionally leading to the assumption of [[suicide]].<ref>[http://www.preskorn.com/columns/0207.html "Column—Fatal Drug-Drug Interaction As a Differential Consideration in Apparent Suicides"] {{webarchive|url=https://web.archive.org/web/20080223185230/http://www.preskorn.com/columns/0207.html |date=February 23, 2008 }}.</ref>
{| class="wikitable"
|+ [[Toxidrome]]s<ref name = Goldfrank98>{{cite book |author=Goldfrank, Lewis R. |title=Goldfrank's toxicologic emergencies |publisher=[[McGraw Hill Education|Appleton & Lange]] |location=Norwalk, CT |year=1998 |isbn=0-8385-3148-2}}</ref>
! Symptoms !! [[blood pressure|Blood<br>Pressure]] !! [[Heart rate]] !! [[respiratory rate|Respiratory<br>Rate]] !! [[Temperature]] !! [[Pupils]] !! [[bowel sounds|Bowel<br>Sounds]] !! [[Diaphoresis]]
 |- 
 | [[Anticholinergic]] || ~<br>{{clarify|date=February 2020}} || up || ~ || up || dilated || down || down
 |- 
 | [[Cholinergic]] || ~ || ~ || unchanged || unchanged || constricted || up || up
 |- 
 | [[Opioid]] || down || down || down || down || constricted || down || down
 |- 
 | [[Sympathomimetic]] || up || up || up || up || dilated || up || up
 |- 
 | [[sedative|Sedative-hypnotic]] || down || down || down || down || ~ || down || down
|}