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Enantioselective synthesis
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===Biocatalysis=== {{Main|Biocatalysis}} Biocatalysis makes use of biological compounds, ranging from isolated [[enzyme]]s to living cells, to perform chemical transformations.<ref>{{GoldBookRef|title=Biocatalysis| file = B00652}}</ref><ref>{{cite book|last1=Faber|first1=Kurt|title=Biotransformations in organic chemistry a textbook|date=2011|publisher=Springer-Verlag|location=Berlin|isbn=978-3-642-17393-6|edition=6th rev. and corr.}}</ref> The advantages of these reagents include very high [[Enantiomeric excess|e.e.s]] and reagent specificity, as well as mild operating conditions and [[Green chemistry|low environmental impact]]. Biocatalysts are more commonly used in industry than in academic research;<ref>{{cite journal|last=Schmid|first=A.|author2=Dordick, J. S. |author3=Hauer, B. |author4=Kiener, A. |author5=Wubbolts, M. |author6= Witholt, B. |journal=Nature|year=2001|volume=409|issue=6817|pages=258โ268|doi=10.1038/35051736|pmid=11196655|title=Industrial biocatalysis today and tomorrow|bibcode=2001Natur.409..258S|s2cid=4340563}}</ref> for example in the production of [[statin]]s.<ref name="statin">{{cite journal|last=Mรผller|first=Michael|title=Chemoenzymatic Synthesis of Building Blocks for Statin Side Chains|journal=Angewandte Chemie International Edition|date=7 January 2005|volume=44|issue=3|pages=362โ365|doi=10.1002/anie.200460852|pmid=15593081|doi-access=free}}</ref> The high reagent specificity can be a problem, however, as it often requires that a wide range of biocatalysts be screened before an effective reagent is found.
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