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Endothelial dysfunction
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=== Endothelial dysfunction and stents === [[Stent]] implantation has been correlated with impaired endothelial function in several studies.<ref name="jte">{{cite journal|pmc=5624345|year=2017|last1=Bedair|first1=T. M|title=Recent advances to accelerate re-endothelialization for vascular stents|journal=Journal of Tissue Engineering|volume=8|pages=2041731417731546|last2=Elnaggar|first2=M. A|last3=Joung|first3=Y. K|last4=Han|first4=D. K|doi=10.1177/2041731417731546|pmid=28989698}}</ref> [[Sirolimus]] eluting stents were previously used because they showed low rates of in-stent [[restenosis]], but further investigation showed that they often impair endothelial function in humans and worsen conditions.<ref name=jte/> One drug used to inhibit restenosis is [[iopromide]]-[[paclitaxel]].<ref>{{Cite journal|last1=Unverdorben|first1=Martin|last2=Vallbracht|first2=Christian|last3=Cremers|first3=Bodo|last4=Heuer|first4=Hubertus|last5=Hengstenberg|first5=Christian|last6=Maikowski|first6=Christian|last7=Werner|first7=Gerald S.|last8=Antoni|first8=Diethmar|last9=Kleber|first9=Franz X.|date=2009-06-16|title=Paclitaxel-coated balloon catheter versus paclitaxel-coated stent for the treatment of coronary in-stent restenosis|journal=Circulation|language=en|volume=119|issue=23|pages=2986β2994|doi=10.1161/circulationaha.108.839282|issn=0009-7322|pmid=19487593|doi-access=free}}</ref>
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