Editing Entactogen (section)

==Side effects==
{{See also|MDMA#Side effects}}

[[Side effect]]s of entactogens like MDMA include [[mydriasis]], [[nystagmus]], [[jaw clenching]], [[bruxism]], [[insomnia]], [[appetite loss]], [[tachycardia]], [[hypertension]], and [[hyperthermia]], among others.<ref name="Oeri2021" /><ref name="Baldo2024" /> Severe [[adverse effect]]s of entactogens like MDMA can include [[dehydration]], hyperthermia, [[seizure]]s, [[rhabdomyolysis]], [[disseminated intravascular coagulation]], [[hyponatremia]], [[acute renal failure]], [[liver injury]], [[serotonin syndrome]], and [[valvular heart disease]].<ref name="Baldo2024" /><ref name="LuethiLiechti2020" /> Entactogens can produce long-lasting [[serotonergic neurotoxicity]]<ref name="BaggottMendelson2001">{{cite book | author1-last=Baggott | author1-first=Matthew | author2-last= Mendelson | author2-first=John | chapter=Does MDMA Cause Brain Damage? | pages=110–145, 396–404 | editor1-last=Holland | editor1-first=J. | title=Ecstasy: The Complete Guide: A Comprehensive Look at the Risks and Benefits of MDMA | publisher=Inner Traditions/Bear | year=2001 | isbn=978-0-89281-857-0 | chapter-url=https://www.erowid.org/chemicals/mdma/mdma_neurotoxicity1.shtml | url=https://books.google.com/books?id=CUCcyklcO00C}}</ref><ref name="SpragueEvermanNichols1998">{{cite journal | vauthors = Sprague JE, Everman SL, Nichols DE | title = An integrated hypothesis for the serotonergic axonal loss induced by 3,4-methylenedioxymethamphetamine | journal = Neurotoxicology | volume = 19 | issue = 3 | pages = 427–441 | date = June 1998 | pmid = 9621349 | doi = | url = https://www.researchgate.net/publication/13663847}}</ref><ref name="Oeri2021" /> and associated [[cognitive deficit|cognitive]] and [[memory deficit]]s as well as [[psychiatric disorder|psychiatric changes]].<ref name="Parrott2002">{{cite journal | vauthors = Parrott AC | title = Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity | journal = Pharmacol Biochem Behav | volume = 71 | issue = 4 | pages = 837–844 | date = April 2002 | pmid = 11888574 | doi = 10.1016/s0091-3057(01)00711-0 | url = }}</ref><ref name="Parrott2013">{{cite journal | vauthors = Parrott AC | title = MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy' users | journal = Neurosci Biobehav Rev | volume = 37 | issue = 8 | pages = 1466–1484 | date = September 2013 | pmid = 23660456 | doi = 10.1016/j.neubiorev.2013.04.016 | url = }}</ref><ref name="AguilarGarcía-PardoParrott2020">{{cite journal | vauthors = Aguilar MA, García-Pardo MP, Parrott AC | title = Of mice and men on MDMA: A translational comparison of the neuropsychobiological effects of 3,4-methylenedioxymethamphetamine ('Ecstasy') | journal = Brain Res | volume = 1727 | issue = | pages = 146556 | date = January 2020 | pmid = 31734398 | doi = 10.1016/j.brainres.2019.146556 | url = }}</ref><ref name="MontgomeryRoberts2022">{{cite journal | vauthors = Montgomery C, Roberts CA | title = Neurological and cognitive alterations induced by MDMA in humans | journal = Exp Neurol | volume = 347 | issue = | pages = 113888 | date = January 2022 | pmid = 34624331 | doi = 10.1016/j.expneurol.2021.113888 | url = https://researchonline.ljmu.ac.uk/id/eprint/15629/3/Montgomery_Roberts_2021%20Review.pdf}}</ref>