Editing Entamoeba (section)

===Fission===
Studying ''Entamoeba invadens'', [[David Biron]] of the [[Weizmann Institute of Science]] and coworkers found that about one third of the cells are unable to separate unaided and recruit a neighboring amoeba (dubbed the "midwife") to complete the fission.<ref>{{cite journal |vauthors=Biron D, Libros P, Sagi D, Mirelman D, Moses E | title = Asexual reproduction: 'Midwives' assist dividing amoebae | year = 2001 | journal = Nature | pmid = 11260701 | volume = 410 | issue = 6827 | pages = 430 | doi = 10.1038/35068628 | bibcode = 2001Natur.410..430B | doi-access = free }}</ref> He writes:

:''When an amoeba divides, the two daughter cells stay attached by a tubular tether which remains intact unless mechanically severed.  If called upon, the neighbouring amoeba midwife travels up to 200 μm towards the dividing amoeba, usually advancing in a straight trajectory with an average velocity of about 0.5 μm/s.  The midwife then proceeds to rupture the connection, after which all three amoebae move on.''

They also reported a similar behavior in ''[[Dictyostelid|Dictyostelium]]''.<ref>{{Cite journal | doi=10.1002/cm.20311| pmid=18688845|title = Chemotaxis-mediated scission contributes to efficient cytokinesis in Dictyostelium| journal=Cell Motility and the Cytoskeleton| volume=65| issue=11| pages=896–903|year = 2008|last1 = Nagasaki|first1 = Akira| last2=Uyeda| first2=Taro Q. P.}}</ref>

Since ''E. histolytica'' does not form cysts in the absence of bacteria, ''E. invadens'' has become used as a model for encystation studies as it will form cysts under axenic growth conditions, which simplifies analysis.<ref>{{Cite journal|last1=Rawat|first1=Aadish|last2=Singh|first2=Parikshit|last3=Jyoti|first3=Anupam|last4=Kaushik|first4=Sanket|last5=Srivastava|first5=Vijay Kumar|date=2020-04-30|title=Averting transmission: A pivotal target to manage amoebiasis|url=https://www.ncbi.nlm.nih.gov/pubmed/32356312|journal=Chemical Biology & Drug Design|volume=96|issue=2|pages=731–744|doi=10.1111/cbdd.13699|issn=1747-0285|pmid=32356312|s2cid=218475533}}</ref> After inducing encystation in ''E. invadens'', DNA replication increases initially and then slows down. On completion of encystation, predominantly tetra-nucleate cysts are formed  along with some uni-, bi- and tri-nucleate cysts.<ref>{{cite journal |vauthors=Singh N, Bhattacharya S, Paul J | title = Entamoeba invadens: Dynamics of DNA synthesis during differentiation from trophozoite to cyst | year = 2010 | pages = 329–33 | issue = 2 | volume = 127 | journal = Experimental Parasitology | pmid = 20727884 | doi = 10.1016/j.exppara.2010.08.013  }}</ref>