Editing Gerald Edelman (section)

===Molecular models of antibody structure===
Using experimental data from his own research and the work of others, Edelman developed molecular models of antibody proteins.<ref>{{Cite journal
| pmid = 14173001
| year = 1964
| last1 = Edelman | first1 = G.
| last2 = Gally | first2 = J.
| title = A Model for the 7S Antibody Molecule
| volume = 51
| issue = 5
| pages = 846–853
| pmc = 300172
| journal = Proceedings of the National Academy of Sciences of the United States of America
| doi = 10.1073/pnas.51.5.846
|bibcode = 1964PNAS...51..846E | doi-access = free
}}</ref> A key feature of these models included the idea that the [[antigen]] binding domains of antibodies ([[Fragment antigen-binding|Fab]]) include [[amino acid]]s from both the [[Immunoglobulin light chain|light]] and [[Immunoglobulin heavy chain|heavy]] protein subunits. The inter-chain disulfide bonds help bring together the two parts of the antigen binding domain.