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Intermediate filament
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=== Type III === [[File:Vimentin.jpg|thumb|[[Vimentin]] fibers in [[fibroblast]]s]] There are four proteins classed as type III intermediate filament proteins, which may form [[homopolymer|homo-]] or [[heteropolymer]]ic proteins. * '''[[Desmin]]''' IFs are structural components of the [[sarcomere]]s in muscle cells and connect different cell organelles like the desmosomes with the cytoskeleton.<ref>{{cite journal | vauthors = Brodehl A, Gaertner-Rommel A, Milting H | title = Molecular insights into cardiomyopathies associated with desmin (DES) mutations | journal = Biophysical Reviews | volume = 10 | issue = 4 | pages = 983β1006 | date = August 2018 | pmid = 29926427 | pmc = 6082305 | doi = 10.1007/s12551-018-0429-0 }}</ref> * '''[[Glial fibrillary acidic protein]]''' (GFAP) is found in [[astrocyte]]s and other [[glia]].{{cn|date=April 2025}} * '''[[Peripherin]]''' found in peripheral neurons.{{cn|date=April 2025}} * '''[[Vimentin]]''', the most widely distributed of all IF proteins, can be found in [[fibroblast]]s, [[leukocytes]], and blood vessel [[endothelial cell]]s. They support the cellular membranes, keep some [[organelle]]s in a fixed place within the [[cytoplasm]], and transmit membrane receptor signals to the nucleus.<ref name="interfil"/> * '''[[Syncoilin]]''' is an atypical type III IF protein.<ref name="Uniprot">{{cite web |title=SYNC β Syncoilin β Homo sapiens (Human) β SYNC gene & protein |url=https://www.uniprot.org/uniprot/Q9H7C4 |website=www.uniprot.org |access-date=20 December 2021 |language=en}}</ref>
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