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Intraocular pressure
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=== Daily variation === Intraocular pressure varies throughout the night and day. The diurnal variation for normal eyes is between 3 and 6 [[mmHg]] and the variation may increase in glaucomatous eyes. During the night, intraocular pressure may not decrease<ref name="pmid21330554">{{cite journal |vauthors = Liu JH, Weinreb RN |title = Monitoring intraocular pressure for 24 h |journal = Br J Ophthalmol |volume = 95 |issue = 5 |pages = 599β600 |date = May 2011 |pmid = 21330554 |doi = 10.1136/bjo.2010.199737 |s2cid = 42736853 }}</ref> despite the slower production of aqueous humour.<ref>{{cite journal |last=Brubaker RF |title=Flow of aqueous humor in humans |journal=Invest Ophthalmol Vis Sci |year=1991 |volume=32 |issue=13 |pages=3145β3166 |pmid=1748546}}</ref> [[Glaucoma]] patients' 24-hour IOP profiles may differ from those of healthy individuals.<ref name="pmid12657596">{{cite journal |vauthors = Liu JH, Zhang X, Kripke DF, Weinreb RN |title = Twenty-four-hour intraocular pressure pattern associated with early glaucomatous changes |journal = Invest. Ophthalmol. Vis. Sci. |volume = 44 |issue = 4 |pages = 1586β90 |date = April 2003 |pmid = 12657596 |doi = 10.1167/iovs.02-0666 |issn=1552-5783 |doi-access = }}</ref>
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