Editing Israel Hanukoglu (section)

===Structures of keratins===
Hanukoglu's career in molecular biology started at the Department of Biochemistry of the [[University of Chicago]] (1980–1983 with [[Elaine Fuchs]]), where he cloned and sequenced cDNAs coding for cytoskeletal proteins, actin<ref name="pmid6842590">{{cite journal | vauthors = Hanukoglu I, Tanese N, Fuchs E | title = Complementary DNA sequence of a human cytoplasmic actin. Interspecies divergence of 3' non-coding regions | journal = Journal of Molecular Biology | volume = 163 | issue = 4 | pages = 673–8 | date = Feb 1983 | pmid = 6842590 | doi = 10.1016/0022-2836(83)90117-1 }}</ref> and alpha keratins.<ref name="1982-Hanukoglu">{{cite journal | vauthors = Hanukoglu I, Fuchs E | title = The cDNA sequence of a human epidermal keratin: divergence of sequence but conservation of structure among intermediate filament proteins. | journal = Cell | volume = 31 | issue = 1 | pages = 243–252 | date=Nov 1982 | doi = 10.1016/0092-8674(82)90424-X | pmid = 6186381 | s2cid = 35796315 |url=https://zenodo.org/record/890743}}</ref><ref name="1983-Hanukoglu">{{cite journal | vauthors = Hanukoglu I, Fuchs E | title = The cDNA sequence of a Type II cytoskeletal keratin reveals constant and variable structural domains among keratins. | journal = Cell | volume = 33 | issue = 3 | pages = 915–924 |date=Jul 1983 | doi = 10.1016/0092-8674(83)90034-X | pmid = 6191871 | s2cid = 21490380 |url=https://zenodo.org/record/890739}}</ref> He elucidated the first structures of cytoskeletal keratin families, and predicted the long helical domains of these proteins. By computerized analysis of amino acid sequences he predicted that the central rod domain of intermediate filament proteins is composed of four helical segments separated by three short linker sequences. Later crystallographic studies have confirmed this as a general model for intermediate filament protein structure.<ref name="pmid22705788">{{cite journal | vauthors = Lee CH, Kim MS, Chung BM, Leahy DJ, Coulombe PA | title = Structural basis for heteromeric assembly and perinuclear organization of keratin filaments | journal = Nature Structural & Molecular Biology | volume = 19 | issue = 7 | pages = 707–15 | date = Jul 2012 | pmid = 22705788 | doi = 10.1038/nsmb.2330 | pmc=3864793}}</ref><ref name="Hanukoglu-2014">{{Cite journal | vauthors = Hanukoglu I, Ezra L | title = Proteopedia: Coiled-coil structure of keratins. | journal = Biochem Mol Biol Educ | volume = 42 | issue = 1 | pages = 93–94 |date=Jan 2014 | doi = 10.1002/bmb.20746 | pmid = 24265184| s2cid = 30720797 | doi-access = free }}</ref>