Open main menu
Home
Random
Recent changes
Special pages
Community portal
Preferences
About Wikipedia
Disclaimers
Incubator escapee wiki
Search
User menu
Talk
Dark mode
Contributions
Create account
Log in
Editing
Kupffer cell
(section)
Warning:
You are not logged in. Your IP address will be publicly visible if you make any edits. If you
log in
or
create an account
, your edits will be attributed to your username, along with other benefits.
Anti-spam check. Do
not
fill this in!
==History== The cells were first observed by [[Karl Wilhelm von Kupffer]] in 1876.<ref>{{cite journal | vauthors = Haubrich WS | title = Kupffer of Kupffer cells | journal = Gastroenterology | volume = 127 | issue = 1 | pages = 16 | date = July 2004 | pmid = 15236167 | doi = 10.1053/j.gastro.2004.05.041 }}</ref> The scientist called them "Sternzellen" (star cells or [[hepatic stellate cell]]) but thought, inaccurately, that they were an integral part of the [[endothelium]] of the liver blood vessels and that they originated from it. In 1898, after several years of research, [[Tadeusz Browicz]] identified them, correctly, as [[macrophage]]s.<ref>{{cite journal | vauthors = Szymańska R, Schmidt-Pospuła M | title = [Studies of liver's reticuloendothelial cells by Tadeusz Browicz and Karl Kupffer. A historical outline] | journal = Archiwum Historii Medycyny | volume = 42 | issue = 3 | pages = 331–6 | year = 1979 | pmid = 386989 }}</ref><ref>{{cite journal | vauthors = Stachura J, Gałązka K | title = History and current status of Polish gastroenterological pathology | journal = Journal of Physiology and Pharmacology | volume = 54 Suppl 3 | pages = 183–92 | date = December 2003 | pmid = 15075472 }}</ref><ref>{{cite journal | vauthors = Śródka A, Gryglewski RW, Szczepański W | title = Browicz or Kupffer cells? | journal = Polish Journal of Pathology | volume = 57 | issue = 4 | pages = 183–5 | year = 2006 | pmid = 17285760 }}</ref><ref>{{cite journal | vauthors = Wake K | title = [Browicz's phagocytic cells and Kupffer's 'so-called stellate cells'] | journal = Kaibogaku Zasshi | volume = 84 | issue = 1 | pages = 17–21 | year = 2009 | pmid = 19413196 }}</ref>
Edit summary
(Briefly describe your changes)
By publishing changes, you agree to the
Terms of Use
, and you irrevocably agree to release your contribution under the
CC BY-SA 4.0 License
and the
GFDL
. You agree that a hyperlink or URL is sufficient attribution under the Creative Commons license.
Cancel
Editing help
(opens in new window)