Editing Lipodystrophy (section)

== Diagnosis ==
The diagnosis is a clinical one, usually established by an experienced endocrinologist.Using a [[Skinfold test|skinfold caliper]] to measure skinfold thickness in various parts of the body or a [[Dual-energy X-ray absorptiometry#Body composition measurement|total body composition scan]] using [[dual-energy X-ray absorptiometry]] may also help identify the subtype.<ref name=":1" /><ref>{{cite journal | vauthors = Guillín-Amarelle C, Sánchez-Iglesias S, Castro-Pais A, Rodriguez-Cañete L, Ordóñez-Mayán L, Pazos M, González-Méndez B, Rodríguez-García S, Casanueva FF, Fernández-Marmiesse A, Araújo-Vilar D | title = Type 1 familial partial lipodystrophy: understanding the Köbberling syndrome | journal = Endocrine | volume = 54 | issue = 2 | pages = 411–421 | date = November 2016 | pmid = 27473102 | doi = 10.1007/s12020-016-1002-x | s2cid = 19689303 | hdl = 10347/32433 | hdl-access = free }}</ref> Dual-energy X-ray absorptiometry may be useful by providing both regional %fat measurements, and direct visualization of fat distribution by means of a "fat shadow".<ref>{{cite journal | vauthors = Meral R, Ryan BJ, Malandrino N, Jalal A, Neidert AH, Muniyappa R, Akıncı B, Horowitz JF, Brown RJ, Oral EA | title = "Fat Shadows" From DXA for the Qualitative Assessment of Lipodystrophy: When a Picture Is Worth a Thousand Numbers | journal = Diabetes Care | volume = 41 | issue = 10 | pages = 2255–2258 | date = October 2018 | pmid = 30237235 | pmc = 6150431 | doi = 10.2337/dc18-0978 }}</ref>  A genetic confirmation is sometimes possible, depending on the subtype. However, in up to 40% of partial lipodystrophy patients, a causative gene has not been identified.<ref name=":0" />