Editing MPTP (section)

==Analogues==
[[Structural analog|Analogue]]s of MPTP include [[2′-NH2-MPTP|2′-NH<sub>2</sub>-MPTP]] (2′-amino-MPTP) and [[2′-CH3-MPTP|2′-CH<sub>3</sub>-MPTP]] (2′-methyl-MPTP).<ref name="MaretTestaJenner1990">{{cite journal | vauthors = Maret G, Testa B, Jenner P, el Tayar N, Carrupt PA | title = The MPTP story: MAO activates tetrahydropyridine derivatives to toxins causing parkinsonism | journal = Drug Metab Rev | volume = 22 | issue = 4 | pages = 291–332 | date = 1990 | pmid = 2253555 | doi = 10.3109/03602539009041087 | url = }}</ref><ref name="ManayeSonsallaBarnett1989">{{cite journal | vauthors = Manaye KF, Sonsalla PK, Barnett G, Heikkila RE, Woodward DJ, Smith WK, German DC | title = 1-Methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'CH3-MPTP)-induced degeneration of mesostriatal dopaminergic neurons in the mouse: biochemical and neuroanatomical studies | journal = Brain Res | volume = 491 | issue = 2 | pages = 307–315 | date = July 1989 | pmid = 2765888 | doi = 10.1016/0006-8993(89)90065-6 | url = }}</ref><ref name="AndrewsMurphy1993">{{cite journal | vauthors = Andrews AM, Murphy DL | title = Sustained depletion of cortical and hippocampal serotonin and norepinephrine but not striatal dopamine by 1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine (2'-NH2-MPTP): a comparative study with 2'-CH3-MPTP and MPTP | journal = J Neurochem | volume = 60 | issue = 3 | pages = 1167–1170 | date = March 1993 | pmid = 8094744 | doi = 10.1111/j.1471-4159.1993.tb03271.x | url = }}</ref>

The [[haloperidol]]-derived monoaminergic neurotoxins [[HPTP]] and [[HPP+|HPP<sup>+</sup>]] are structurally related to MPTP.<ref name="CastagnoliCastagnoliVanderSchyf1999">{{cite journal | vauthors = Castagnoli N, Castagnoli KP, Van der Schyf CJ, Usuki E, Igarashi K, Steyn SJ, Riker RR | title = Enzyme-catalyzed bioactivation of cyclic tertiary amines to form potential neurotoxins | journal = Pol J Pharmacol | volume = 51 | issue = 1 | pages = 31–38 | date = 1999 | pmid = 10389142 | doi = | url = }}</ref>