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Maturation promoting factor
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===Overview of functions=== * Triggers the formation of mitotic spindle through microtubule instability. * Promotes mitosis i.e. chromatin condensation through phosphorylation of condensins. * The three lamins present in the nuclear lamina, lamin A, B & C, are phosphorylated by MPF at serine amino residues. This leads to depolymerisation of the nuclear lamina & breakdown of nuclear envelope into small vesicles. * Causes phosphorylation of GM130, which leads to the fragmentation of the Golgi and the ER.
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