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Methicillin
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==History== Methicillin was developed by [[Beecham (pharmaceutical company)|Beecham]] in 1959.<ref name="Dutfield2009">{{cite book| first = Graham | last = Dutfield | name-list-style = vanc |title=Intellectual property rights and the life science industries: past, present and future|url=https://books.google.com/books?id=hnleY38aUxYC&pg=PA140|access-date=18 November 2010|date=30 July 2009|publisher=World Scientific|isbn=978-981-283-227-6|pages=140β}}</ref> It was previously used to treat [[infection]]s caused by susceptible gram-positive bacteria, in particular, [[penicillinase]]-producing organisms such as ''[[Staphylococcus aureus]]'' that would otherwise be resistant to most penicillins. Its role in therapy has been largely replaced by [[oxacillin]] (used for clinical antimicrobial susceptibility testing), [[flucloxacillin]] and [[dicloxacillin]], but the term [[methicillin-resistant Staphylococcus aureus]] (MRSA) continues to be used to describe ''S. aureus'' strains resistant to all penicillins.<ref>{{cite journal | vauthors = Newsom SW | title = MRSA--past, present, future | journal = Journal of the Royal Society of Medicine | volume = 97 | issue = 11 | pages = 509β10 | date = November 2004 | pmid = 15520143 | pmc = 1079642 | doi = 10.1177/014107680409701101 }}</ref>
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