Editing Microtome (section)

===Sledge ===
[[File:Sledge microtome.jpg|thumb|left|A sled microtome]]

A sledge microtome is a device where the sample is placed into a fixed holder (shuttle), which then moves backwards and forwards across a knife. Modern sled microtomes have the sled placed upon a linear bearing, a design that allows the microtome to readily cut many coarse sections.<ref name="Lang">{{Cite book|author=Gudrun Lang |title=''Histotechnik. Praxislehrbuch für die Biomedizinische Analytik.'' (Histology : practical textbook for analytical biomedicine)|publisher=Springer, Wien/New York|year= 2006|isbn=978-3-211-33141-5}}</ref> By adjusting the angles between the sample and the microtome knife, the pressure applied to the sample during the cut can be reduced.<ref name="Lang" /> Typical applications for this design of microtome are of the preparation of large samples, such as those embedded in paraffin for biological preparations. Typical cut thickness achievable on a sledge microtome is between 1 and 60&nbsp;μm.

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