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Monoamine transporter
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===Serotonin transporter (SERT)=== {{Main|Serotonin transporter}} SERT is responsible for the reuptake of extracellular serotonin (5-HT) in a Na <sup>+</sup>/Cl <sup>β</sup> -dependent process.<ref name=rama/> In the CNS, SERT is found localized in the [[cerebral cortex]], CA1 and CA3 regions of the hippocampus, as well as the median and dorsal [[raphe nuclei]]. In the PNS, SERT is localized to the intestinal tract, [[adrenal glands]], placenta, lung, and platelets .<ref name=Torres/><ref name=rama/> Expression of SERT in platelets is used as a means to reacquire 5-HT from the extracellular environment and later used in platelet activation. Regulation of SERT has been linked to acute depletion of intracellular Ca Na <sup>2+</sup>, [[calmodulin]] inhibition, CaMKII, [[Src (gene)|Src]], [[p38 MAP kinase]], PKC, and activation of [[Nitric oxide synthase|NOS]]/[[cyclic guanosine monophosphate|cGMP]].<ref name=rama/>
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