Editing Monocyte (section)

===In mice===
In mice, monocytes can be divided in two subpopulations. Inflammatory monocytes ([[CX3CR1]]<sup>low</sup>, [[CCR2]]<sup>pos</sup>, [[Ly6C]]<sup>high</sup>, [[PD-L1]]<sup>neg</sup>), which are equivalent to human classical CD14<sup>++</sup> CD16<sup>−</sup> monocytes and resident monocytes ([[CX3CR1]]<sup>high</sup>, [[CCR2]]<sup>neg</sup>, [[Ly6C]]<sup>low</sup>, [[PD-L1]]<sup>pos</sup>), which are equivalent to human non-classical CD14<sup>+</sup> CD16<sup>+</sup> monocytes. Resident monocytes have the ability to patrol along the endothelium wall in the steady state and under inflammatory conditions.<ref>{{cite journal |last1=Carlin |first1=Leo M. |last2=Stamatiades |first2=Efstathios G. |last3=Auffray |first3=Cedric |last4=Hanna |first4=Richard N. |last5=Glover |first5=Leanne |last6=Vizcay-Barrena |first6=Gema |last7=Hedrick |first7=Catherine C. |last8=Cook |first8=H. Terence |last9=Diebold |first9=Sandra |last10=Geissmann |first10=Frederic |title=Nr4a1-Dependent Ly6Clow Monocytes Monitor Endothelial Cells and Orchestrate Their Disposal |journal=Cell |date=April 2013 |volume=153 |issue=2 |pages=362–375 |doi=10.1016/j.cell.2013.03.010 |pmid=23582326 |pmc=3898614 }}</ref><ref>{{cite journal |last1=Auffray |first1=Cedric |last2=Fogg |first2=Darin |last3=Garfa |first3=Meriem |last4=Elain |first4=Gaelle |last5=Join-Lambert |first5=Olivier |last6=Kayal |first6=Samer |last7=Sarnacki |first7=Sabine |last8=Cumano |first8=Ana |last9=Lauvau |first9=Gregoire |last10=Geissmann |first10=Frederic |title=Monitoring of Blood Vessels and Tissues by a Population of Monocytes with Patrolling Behavior |journal=Science |date=3 August 2007 |volume=317 |issue=5838 |pages=666–670 |doi=10.1126/science.1142883 |pmid=17673663 |bibcode=2007Sci...317..666A |s2cid=46067303 }}</ref><ref>{{cite journal |last1=Imhof |first1=Beat A. |last2=Jemelin |first2=Stephane |last3=Ballet |first3=Romain |last4=Vesin |first4=Christian |last5=Schapira |first5=Marc |last6=Karaca |first6=Melis |last7=Emre |first7=Yalin |date=16 August 2016 |title=CCN1/CYR61-mediated meticulous patrolling by Ly6C low monocytes fuels vascular inflammation |journal=[[Proceedings of the National Academy of Sciences]] |volume=113 |issue=33 |pages=E4847–E4856 |doi=10.1073/pnas.1607710113 |pmc=4995973 |pmid=27482114 |bibcode=2016PNAS..113E4847I |doi-access=free}}</ref><ref>{{cite journal |last1=Bianchini |first1=Mariaelvy |last2=Duchêne |first2=Johan |last3=Santovito |first3=Donato |last4=Schloss |first4=Maximilian J. |last5=Evrard |first5=Maximilien |last6=Winkels |first6=Holger |last7=Aslani |first7=Maria |last8=Mohanta |first8=Sarajo K. |last9=Horckmans |first9=Michael |last10=Blanchet |first10=Xavier |last11=Lacy |first11=Michael |date=21 June 2019 |title=PD-L1 expression on nonclassical monocytes reveals their origin and immunoregulatory function |journal=[[Science Immunology]] |volume=4 |issue=36 |pages=eaar3054 |doi=10.1126/sciimmunol.aar3054 |pmid=31227596 |doi-access=free |last12=von Hundelshausen |first12=Philipp |last13=Atzler |first13=Dorothee |last14=Habenicht |first14=Andreas |last15=Gerdes |first15=Norbert |last16=Pelisek |first16=Jaroslav |last17=Ng |first17=Lai Guan |last18=Steffens |first18=Sabine |last19=Weber |first19=Christian |last20=Megens |first20=Remco T. A. |s2cid=195259881}}</ref>