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Orthostatic hypotension
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===Medication=== [[File:Tetrahydrocannabinol.svg|thumb|160 px|Tetrahydrocannabinol]] Orthostatic hypotension can be a side effect of certain [[antidepressants]], such as [[tricyclic antidepressant|tricyclics]]<ref name=pmid16290952>{{cite journal | vauthors = Jiang W, Davidson JR | title = Antidepressant therapy in patients with ischemic heart disease | journal = American Heart Journal | volume = 150 | issue = 5 | pages = 871β881 | date = November 2005 | pmid = 16290952 | doi = 10.1016/j.ahj.2005.01.041 }}</ref> or [[monoamine oxidase inhibitor]]s (MAOIs)<ref name=pmid12412837>{{cite journal | vauthors = Jones RT | title = Cardiovascular system effects of marijuana | journal = Journal of Clinical Pharmacology | volume = 42 | issue = S1 | pages = 58Sβ63S | date = November 2002 | pmid = 12412837 | doi = 10.1002/j.1552-4604.2002.tb06004.x | s2cid = 12193532 }}</ref> Alcohol can potentiate orthostatic hypotension to the point of [[syncope (medicine)|syncope]].<ref name=pmid10653831>{{cite journal | vauthors = Narkiewicz K, Cooley RL, Somers VK | title = Alcohol potentiates orthostatic hypotension : implications for alcohol-related syncope | journal = Circulation | volume = 101 | issue = 4 | pages = 398β402 | date = February 2000 | pmid = 10653831 | doi = 10.1161/01.CIR.101.4.398 | doi-access = free }}</ref> Orthostatic hypotension can also be a side effect of [[alpha-1 blocker]]s (alpha<sub>1</sub> adrenergic blocking agents). Alpha<sub>1</sub> blockers inhibit vasoconstriction normally initiated by the [[baroreceptor reflex]] upon postural change and the subsequent drop in pressure.<ref>{{cite web | vauthors = Shea MJ, Thompson AD | title = Orthostatic Hypotension | url = https://www.msdmanuals.com/professional/cardiovascular-disorders/symptoms-of-cardiovascular-disorders/orthostatic-hypotension | work = [[Merck Manual]] }}</ref> Other [[antihypertensive drug|antihypertensive medications]] may also cause orthostatic hypotension, in addition to [[anticholinergic]]s, [[dopaminergic]] drugs, [[opiates]] and [[psychoactive drug|psychoactive medications]].<ref name="AAFP Kim" />
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