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Overwhelming post-splenectomy infection
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===Vaccination=== The [[Centers for Disease Control and Prevention]]'s annual vaccine recommendations includes specifics for individuals without a functioning spleen.<ref>{{cite web |title=2018 Adult Schedule by Health Conditions in Easy-to-read Format for Patients |url=https://www.cdc.gov/vaccines/schedules/easy-to-read/adult-conditions-easyread.html |website=Centers for Disease Control and Prevention |access-date=19 June 2018}}</ref> [[The Green Book (immunisation guidance, UK)]] in chapter 7<ref>{{cite web |title=Immunisation of individuals with underlying medical conditions: the green book, chapter 7 |date=10 January 2020 |url=https://www.gov.uk/government/publications/immunisation-of-individuals-with-underlying-medical-conditions-the-green-book-chapter-7 |access-date=2023-08-24}}</ref> covers immunisation of people with underlying medical conditions that affect immunity which includes asplenic patients. As there are a range of different pneumococcal vaccines, the patient should be offered the most up to date ones (typically 23 valent polysaccharide vaccine and 13 valent conjugate vaccine), if they have not had them already as part of standard schedule. Repeat doses are recommended in patients without a spleen. The CDC recommends against live vaccines and has specific advice for travellers, which includes malaria avoidance for asplenic individuals.<ref>{{cite web |author1=Camille Nelson Kotton |author2=Andrew T. Kroger |author3=David O. Freedman |author-link1=Immunocompromised Travelers |title=Advising Travelers with Specific Needs |url=https://wwwnc.cdc.gov/travel/yellowbook/2018/advising-travelers-with-specific-needs/immunocompromised-travelers |website=Travelers' Health |access-date=25 October 2018}}</ref>
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