Editing Patrick Dempsey (section)

===2005–2015: Stardom and ''Grey's Anatomy''===
{{Main|Grey's Anatomy}}
Dempsey has received significant public attention for his role as [[Derek Shepherd|Dr. Derek "McDreamy" Shepherd]] in the medical drama ''[[Grey's Anatomy]]'' opposite [[Ellen Pompeo]]. Before landing the role, Dempsey auditioned for the role of [[Dr. Chase]] on another medical show, ''[[House (TV series)|House]]''. He also appeared in two episodes of the later ''Grey''<nowiki/>'''s'' spinoff ''[[Private Practice (TV series)|Private Practice]]'', playing the same character of Dr. Shepherd.<ref name="imdb">{{IMDb name|1131}}</ref> The relationship his character had with Meredith Grey ([[Ellen Pompeo]]) on screen has received a lot of praise and positive reactions.

In 2007, Dempsey starred in the [[Disney]] film ''[[Enchanted (2007 film)|Enchanted]]'', and the [[Paramount Pictures]] film ''[[Freedom Writers]]'', where he reunited with his ''Iron Jawed Angels'' co-star [[Hilary Swank]]. He also voiced the character [[Kenai (Brother Bear)|Kenai]] in ''[[Brother Bear]]'' sequel ''[[Brother Bear 2]]'', replacing [[Joaquin Phoenix]]. Other roles Dempsey appeared in during this time include the 2008 film ''[[Made of Honor]]'' as Tom, and the 2010 romantic comedy ''[[Valentine's Day (2010 film)|Valentine's Day]]''; the latter film follows five interconnecting stories about Los Angelinos anticipating (or in some cases dreading) the holiday of love.<ref>{{cite news|author=Matt Mitovich|title=Grey's Stars Dempsey and Dane Celebrate Valentine's Day|url=http://movies.tvguide.com/Movie-News/Dempsey-Dane-Valentines-1007819.aspx|work=TVGuide.com|date=July 8, 2009|access-date=July 8, 2009|url-status=dead|archive-url=https://web.archive.org/web/20090711081827/http://movies.tvguide.com/Movie-News/Dempsey-Dane-Valentines-1007819.aspx|archive-date=July 11, 2009}}</ref> Universal Pictures acquired the rights to the prize-winning novel ''[[The Art of Racing in the Rain]]'' in July 2009, for Dempsey to star in.<ref>{{citation |author=Fleming, Michael|title=Dempsey shifts gears for Universal|journal=Variety|date=July 15, 2009}}</ref> The film instead starred Milo Ventimiglia.<ref>{{citation|author=Boucher, Geoff|title=Dempsey hopes to leave 'McDreamy' in rearview|journal=Chicago Tribune|date=July 25, 2011}}</ref> He starred as Dylan Gould in ''[[Transformers: Dark of the Moon]]'' (2011).<ref>{{cite web|url=http://www.nationalledger.com/artman/publish/article_272631647.shtml|title=Patrick Dempsey & Transformers – McDreamy's Transforming Role|work=National Ledger|date=May 6, 2010|access-date=May 12, 2010|url-status=dead|archive-url=https://web.archive.org/web/20100509152026/http://www.nationalledger.com/artman/publish/article_272631647.shtml|archive-date=May 9, 2010}}</ref><ref>{{cite web|url=http://www.accesshollywood.com/patrick-dempsey-from-mcdreamy-to-transformers-3_article_31946|title=Patrick Dempsey: From McDreamy To 'Transformers 3'|publisher=Access Hollywood|date=May 11, 2010|access-date=April 22, 2011}}</ref>

In January 2014, he signed a two-year contract to remain on ''Grey's Anatomy'', then in its tenth season, that would ensure his participation for potential 11th and 12th seasons.<ref>{{cite web|last1=Goldberg|first1=Lesley|title='Grey's Anatomy's' Patrick Dempsey, Ellen Pompeo Ink New Two-Year Deals|url=https://www.hollywoodreporter.com/live-feed/greys-anatomys-patrick-dempsey-ellen-673644|website=[[The Hollywood Reporter]]|access-date=April 25, 2014|date=January 23, 2014}}</ref><ref>{{cite web|last1=Wagmeister|first1=Elizabeth|title='Grey's Anatomy': Patrick Dempsey Officially Leaving After 11 Seasons|url=https://variety.com/2015/tv/news/patrick-dempsey-leaving-greys-anatomy-derek-dies-1201478891/|website=[[Variety (magazine)|Variety]]|access-date=April 25, 2015|date=April 23, 2015}}</ref><ref>{{cite magazine|last1=Rice|first1=Lynette|title=Grey's Anatomy star Patrick Dempsey on tonight's shocking twist -- exclusive|url=https://www.ew.com/article/2015/04/23/patrick-dempsey-interview|magazine=[[Entertainment Weekly]]|access-date=April 25, 2015|date=April 24, 2015}}</ref> Dempsey was nominated for [[Golden Globe Award for Best Actor – Television Series Drama|Best Actor – Television Series Drama]] at the 2006 [[Golden Globe Awards]] for the role. His success on the show has led to his becoming a spokesman for Mazda and State Farm Insurance.<ref>{{cite news|title=State Farm Commercial Guy|url=http://www.insurancezing.com/state-farm/commercial.html|access-date=August 30, 2014}}</ref><ref>{{cite web|title=Mazda Man Patrick Dempsey Interview| date=December 16, 2009 |url=https://www.youtube.com/watch?v=Nx_4ul4wtjE| archive-url=https://ghostarchive.org/varchive/youtube/20211029/Nx_4ul4wtjE| archive-date=October 29, 2021|publisher=[[YouTube]]|access-date=August 30, 2014}}{{cbignore}}</ref> [[BuddyTV]] ranked him #1 on its list of "TV's Sexiest Men of 2011".<ref>{{cite web|url=http://www.buddytv.com/slideshows/white-collar/tvs-100-sexiest-men-of-2011-29104.aspx|title=TV's 100 Sexiest Men of 2011|date=December 7, 2011 |publisher=[[BuddyTV]]|access-date=March 9, 2012}}</ref> In November 2020, Dempsey appeared as Derek Shepherd at the start of the series' 17th season for the first time since the character had died in April 2015.<ref>{{cite web|last1=Andreeva|first1=Nellie|title='Grey's Anatomy' Shocker: Krista Vernoff, Ellen Pompeo & Patrick Dempsey On Season 17 Premiere's Dream Reunion & More|url=https://deadline.com/2020/11/patrick-dempsey-greys-anatomy-return-shocker-season-premiere-interview-derek-meredith-reunion-fate-1234613511/|website=[[Deadline Hollywood]]|access-date=November 12, 2020|date=November 21, 2020}}</ref>