Editing Polypill (section)

====Treating diabetes and metabolic syndrome====

Polypills have been proposed for managing [[diabetes]] (and potentially for [[pre-diabetes]]).<ref>{{cite journal |author=Kuehn BM |title="Polypill" could slash diabetes risks |journal=JAMA |volume=296 |issue=4 |pages=377–80 |date=July 2006 |pmid=16868284 |doi=10.1001/jama.296.4.377}}</ref>

[[Diabetes]] - particularly [[Type II diabetes]] - is a major cause of morbidity and mortality. Diabetes also contributes substantially to cardiovascular risk, yet some ingredients appropriate for a cardiovascular polypill may not be advisable for patients with diabetes (such as [[beta-blockers]] and [[thiazide diuretics]]).  A polypill for diabetes could include a [[statin]] (to reduce [[LDL cholesterol]] and for their [[anti-inflammatory]] properties), an [[ACE inhibitor]] (for blood pressure control and to protect the [[kidneys]]), [[aspirin]] (for anti[[platelet]] and anti-inflammatory properties), and [[metformin]] (a medication for diabetes that is also associated with weight loss).